Aboulenein, W., Abd Aldayem, T., Elhedeny, D. (2023). THE ROLE OF LOCAL ESTROGEN THERAPY IN POSTMENOPAUSAL OVERACTIVE BLADDER. ALEXMED ePosters, 5(1), 12-13. doi: 10.21608/alexpo.2023.187538.1547
Wafaa Aboulenein; Tamer Abd Aldayem; Dina Hesham Abd El-Galil Elhedeny. "THE ROLE OF LOCAL ESTROGEN THERAPY IN POSTMENOPAUSAL OVERACTIVE BLADDER". ALEXMED ePosters, 5, 1, 2023, 12-13. doi: 10.21608/alexpo.2023.187538.1547
Aboulenein, W., Abd Aldayem, T., Elhedeny, D. (2023). 'THE ROLE OF LOCAL ESTROGEN THERAPY IN POSTMENOPAUSAL OVERACTIVE BLADDER', ALEXMED ePosters, 5(1), pp. 12-13. doi: 10.21608/alexpo.2023.187538.1547
Aboulenein, W., Abd Aldayem, T., Elhedeny, D. THE ROLE OF LOCAL ESTROGEN THERAPY IN POSTMENOPAUSAL OVERACTIVE BLADDER. ALEXMED ePosters, 2023; 5(1): 12-13. doi: 10.21608/alexpo.2023.187538.1547
THE ROLE OF LOCAL ESTROGEN THERAPY IN POSTMENOPAUSAL OVERACTIVE BLADDER
1Obstetrics and Gynecology Department, Faculty of Medicine, Alexandria University, Egypt
2Obstetric and Gynecology department, faculty of Medicine, Alexandria University, Alexandria
3Department of Obstetrics and Gynecology, Faculty of Medicine - Alexandria University
Abstract
Overactive bladder (OAB) is relatively common in the general population but more common in women, especially in postmenopausal women with the genitourinary syndrome of menopause (GSM). AIM OF THE WORK: The aim of this study was to assess the efficacy of local estrogen hormone in improving the OAB symptoms in postmenopausal women with GSM. PATIENTS AND METHODS: A randomized, double-blind, placebo-controlled was carried out on 56 patients with GSM with the complaints consistent with OAB and recruited from the urogynecology out-patient clinic, Department of obstetrics and gynecology at El Shatby Alexandria University Hospital. Patients were divided into two groups: Group (A) received 0.5 g of conjugated estrogen (Premarin vaginal cream) twice weekly for 8 weeks, and group (B) received a placebo at the same dose. All subjects were subjected to full history taking, questionnaire derived from the UDI-6 and IIQ-7, clinical examination and investigations including complete urine analysis and urodynamic studies. After 8 weeks, patients in both groups were assessed again by a UDI-6 and IIQ-7 and urodynamics, and the results of both groups were compared.
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