THE ROLE OF LOCAL ESTROGEN THERAPY IN POSTMENOPAUSAL OVERACTIVE BLADDER

Document Type : Preliminary preprint short reports of original research

Authors

1 Obstetrics and Gynecology Department, Faculty of Medicine, Alexandria University, Egypt

2 Obstetric and Gynecology department, faculty of Medicine, Alexandria University, Alexandria

3 Department of Obstetrics and Gynecology, Faculty of Medicine - Alexandria University

Abstract

Overactive bladder (OAB) is relatively common in the general population but more common in women, especially in postmenopausal women with the genitourinary syndrome of menopause (GSM).
AIM OF THE WORK:
The aim of this study was to assess the efficacy of local estrogen hormone in improving the OAB symptoms in postmenopausal women with GSM.
PATIENTS AND METHODS:
A randomized, double-blind, placebo-controlled was carried out on 56 patients with GSM with the complaints consistent with OAB and recruited from the urogynecology out-patient clinic, Department of obstetrics and gynecology at El Shatby Alexandria University Hospital. Patients were divided into two groups: Group (A) received 0.5 g of conjugated estrogen (Premarin vaginal cream) twice weekly for 8 weeks, and group (B) received a placebo at the same dose. All subjects were subjected to full history taking, questionnaire derived from the UDI-6 and IIQ-7, clinical examination and investigations including complete urine analysis and urodynamic studies. After 8 weeks, patients in both groups were assessed again by a UDI-6 and IIQ-7 and urodynamics, and the results of both groups were compared.

Keywords

ALEXMED ePosters
Volume 5, Issue 1
January 2023
Pages 12-13

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