ASSESSMENT OF SOME SERUM INFLAMMATORY MARKERS AND HORMONE PROFILE AMONG PATIENTS WITH ERECTILE DYSFUNCTION

Sorour, Osama; Abdelmageed, Salma Samir; Abouelnaga, Shady; Bosco, NDAGIJIMANA Jean

doi:10.21608/alexpo.2022.170564.1493

ASSESSMENT OF SOME SERUM INFLAMMATORY MARKERS AND HORMONE PROFILE AMONG PATIENTS WITH ERECTILE DYSFUNCTION

Document Type : Preliminary preprint short reports of original research

Authors

¹ Dermatology, Venereology & Andrology, Faculty of Medicine, University of Alexandria

² Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University

³ Department of clinical and chemical pathology, Faculty of Medicine, University of Alexandria

⁴ Dermatology, Venereology &amp; Andrology, Faculty of Medicine, University of Alexandria

10.21608/alexpo.2022.170564.1493

Abstract

Erectile dysfunction (ED) is characterized by consistent inability to achieve and maintain sufficient erection for satisfactory sexual intercourse. Subclinical inflammation with raised inflammatory markers including CRP, NLR, PLR among others have been associated with cardiovascular disease/coronary artery disease and male erectile dysfunction (ED) in addition to hormonal changes including serum estradiol, testosterone & prolactin. To our knowledge there is a paucity of studies comparing Penile Color duplex Doppler ultrasound, inflammatory markers and hormonal profile among patients with ED. Hence, this study aims to assess some serum inflammatory markers and hormone profile among patients with erectile dysfunction.
Aim of work
The aim of this study was to assess some inflammatory, serum hormonal profile among patients with ED.
Patients and Methods
It’s a case control study. This study was conducted on 25 patients diagnosed with ED who attended the Andrology clinic of the Main University Hospital and 15 healthy men as control group with normal erectile function. Ethical approval and consent were issued. All subjects of the study were assessed with comprehensive history, physical exam and blood sampling for complete blood count and hormonal profile analysis. Patients with ED additionally were assessed using the International Index of Erectile Function score (IIEF-5) and penile Doppler ultrasound.

Keywords