PERI-OPERATIVE PREDICTORS PREDISPOSING TO POST-OPERATIVE ATRIAL FIBRILLATION AFTER CORONARY ARTERY BYPASS SURGERY

Document Type : Preliminary preprint short reports of original research

Authors

1 Cardiothoracic Surgery Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt

2 Hepatobiliarypancreatic unit, Surgery department, Faculty of medicine, Alexandria university

3 Cardiothoracic Surgery Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

4 Department of Cardiothoracic Surgery, Faculty of Medicine Alexandria University

Abstract

Postoperative atrial fibrillation (POAF) is a common complication following cardiovascular surgery, with an incidence of 30% after CABG, 40% after valve surgery, and 50% after combined procedures. It typically peaks 2-3 days post-surgery and is associated with hemodynamic instability, thromboembolism, prolonged hospital stay, ICU readmission, organ failure, increased healthcare costs, and mortality.

The exact pathophysiology of POAF is complex, involving inflammation, oxidative stress, autonomic dysfunction, and electrophysiological remodeling, influenced by preoperative, intraoperative, and postoperative factors. Identifying high-risk patients is crucial for early prevention and management to improve outcomes and reduce complications.

Risk factors for POAF include advanced age, obesity, hypertension, diabetes mellitus, and COPD, though definitive predictors remain unclear.

The aim of the study was to identify perioperative risk factors contributing to POAF after CABG and assess its impact on patient outcomes.



AIM:

The aim of this study was to detect peri-operative risk factors that predispose to development of post-operative atrial fibrillation after Coronary Artery Bypass Craft (CABG), and to asses the impact of atrial fibrillation on outcome.

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