CORRELATION BETWEEN MULTI-PARAMETRIC MAGNETIC RESONANCE IMAGING AND RADICAL PROSTATECTOMY OUTCOME

Ramadan, Adel; Zakarea Assem, Akram; Alsaadany, Omnia Ezz Eldin Fathy; Mo&iuml;se, Kwabene

doi:10.21608/alexpo.2025.412571.2253

CORRELATION BETWEEN MULTI-PARAMETRIC MAGNETIC RESONANCE IMAGING AND RADICAL PROSTATECTOMY OUTCOME

Document Type : Preliminary preprint short reports of original research

Authors

¹ Department of Radiodiagnosis and Intervention, Faculty of Medicine, University of Alexandria

² Department of urology , Faculty of Medicine, Alexandria University

³ Department of Radiodiagnosi, Faculty of Medicine, University of Alexandria

⁴ Department of Radiodiagnosis and Intervention, Alexandria University, Alexandria, Egypt.

10.21608/alexpo.2025.412571.2253

Abstract

Introduction
According to the American Cancer Society, Prostate cancer (PCa) is among the most common malignancies in males, with an estimation of approximately 248,530 new cases and 34,130 deaths in the United States alone in 2021.
Multi-parametric Magnetic Resonance Imaging (mp-MRI) is a technique aiming to improve the diagnostic sensitivity of prostate biopsy and is utilized in programs such as active surveillance and for surgical planning. It can be utilized in detection of PCa and identification of extraprostatic disease.
Radical prostatectomy is the commonest utilized therapeutic approach in patients diagnosed with a clinically localized PCa.

Aim of the work
The aim of this study is to correlate between mp-MRI and radical prostatectomy outcome.

Patients and Methods
This study included 50 patients who underwent radical prostatectomy after having done mp-MRI at Alexandria Main University Hospital from 2016 to 2022. The following informations collected from the files of patients were entered into a master table :
• Laboratory investigation : Prostate Specific Antigen (PSA)
• Mp-MRI Prostate report : o Prostate measurement. o Definite suspicious lesions analysis on T2WI, DWI and DCE sequences with final PI-RADS category. o Extraprostatic Extension (EPE). o Pelvic lymph nodes. o Visualized portion of the axial skeleton.
• Histopathological results : o Prostate size. o Histologic type of tumor. o Histologic grade. o Tumor size. o Location of dominant nodule. o EPE. o Lymphovascular invasion. o Perineural invasion.

Keywords