ASSESSMENT OF MACULAR PERFUSION CHANGES AFTER PHACOEMULSIFICATION BY OPTICAL COHERENCE TOMOGRAPHY-ANGIOGRAPHY

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of Ophthalmology, faculty of Medicine, Alexandria University

2 Department of Ophthalmology, Faculty of Medicine, Alexandria University

Abstract

FAZ is a capillary-free area which surrounded by interconnected retinal capillary beds which sharply demarcating the avascular area. It is considered an anatomical reference mark for locating the point of fixation. The size of the FAZ reflects the status of the microcapillarycirculation in the foveal area. The FAZ area is strongly positively correlated with the degree of capillary nonperfusion in several retinovascular diseases. Also, the FAZ area quantification has a great value in monitoring the retinovascular disease progression as in diabetic retinopathy
Any trauma associated with cataract surgery causes disturbance in the blood- aqueous barrier (BAB) and can lead to an inflammatory response and release of the inflammatory mediators like prostaglandins and leukotrienes from arachidonic acid. Prostaglandins are released naturally from the iris and ciliary body and migrate to the retina after surgery. The inflammatory response can cause the activation of the immune system, including neutrophils, macrophages, T lymphocytes and inflammatory mediators.
AIM:
The aim of this study was to evaluate macular perfusion changes and foveal avascular zone after uneventful cataract surgery using optical coherence tomography angiography.

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