Saleh, H., Agmeya, A., Ahmed, Z., Abohashem, M. (2025). TRIGGER DAY SERUM PROGESTERONE LEVEL VERSUS PROGESTERONE TO FOLLICLE RATIO REGARDING REPRODUCTIVE OUTCOME OF ANTAGONIST PROTOCOL. ALEXMED ePosters, 7(2), 42-43. doi: 10.21608/alexpo.2025.385154.2170
Hisham Ali Saleh; Abdel Fattah Agmeya; Ziad Mansour Ahmed; Mohamed Gamal Elsayed Mohamed Abohashem. "TRIGGER DAY SERUM PROGESTERONE LEVEL VERSUS PROGESTERONE TO FOLLICLE RATIO REGARDING REPRODUCTIVE OUTCOME OF ANTAGONIST PROTOCOL". ALEXMED ePosters, 7, 2, 2025, 42-43. doi: 10.21608/alexpo.2025.385154.2170
Saleh, H., Agmeya, A., Ahmed, Z., Abohashem, M. (2025). 'TRIGGER DAY SERUM PROGESTERONE LEVEL VERSUS PROGESTERONE TO FOLLICLE RATIO REGARDING REPRODUCTIVE OUTCOME OF ANTAGONIST PROTOCOL', ALEXMED ePosters, 7(2), pp. 42-43. doi: 10.21608/alexpo.2025.385154.2170
Saleh, H., Agmeya, A., Ahmed, Z., Abohashem, M. TRIGGER DAY SERUM PROGESTERONE LEVEL VERSUS PROGESTERONE TO FOLLICLE RATIO REGARDING REPRODUCTIVE OUTCOME OF ANTAGONIST PROTOCOL. ALEXMED ePosters, 2025; 7(2): 42-43. doi: 10.21608/alexpo.2025.385154.2170
TRIGGER DAY SERUM PROGESTERONE LEVEL VERSUS PROGESTERONE TO FOLLICLE RATIO REGARDING REPRODUCTIVE OUTCOME OF ANTAGONIST PROTOCOL
1Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University
2Department of Obstetrics and Gynecology, Endoscopy Unit, Faculty of Medicine, Alexandria University, Egypt
3Department of Obstetrics and Gynecology, Faculty of Medicine, University of Alexandria
Abstract
Progesterone levels in the serum on the day of HCG trigger are the simplest predictor of reproductive success, although they are not reliable. In the late follicular stage, serum P levels vary depending on the ovarian response since many follicles develop during the COS protocol with elevated estradiol levels. Depending on the ovarian response, different studies define the threshold for high P levels differently, falling between 0.4 ng/ml to 3 ng/ml. Therefore, we could be better use another reproductive outcome predictive factor. Progesterone to follicle ratio was employed in this study as a predictor of the outcome of the ICSI cycle. In this case, we used the follicle count (≥14 mm on the day of HCG) as a marker of available embryos and an indicative of the ovarian response. We also connected this figure to the level of serum progesterone, which indicates endometrial receptivity.
AIM OF THE WORK: The purpose of this research is to evaluate the progesterone to follicle ratio's predictive value for the reproductive outcome (clinical pregnancy) after fresh embryo transfer in female patients receiving ICSI cycles with GnRH antagonists at private IVF centers. And determining whether this ratio is a better way to predict clinical pregnancy rates than measuring isolated serum progesterone on the day that the oocytes finally mature, is the study's secondary goal.
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