FAILURE PATTERNS OF HEAD AND NECK CANCER PATIENTS TREATED WITH CHEMOTHERAPY AND RADIOTHERAPY

Document Type : Preliminary preprint short reports of original research

Authors

1 Alexandria Clinical Oncology Department, Faculty of Medicine, Alexandria University, Alexandria Egypt.

2 Department of Clinical Oncology and Nuclear Medicine, University of Alexandria, Alexandria, Egypt

3 Department of Clinical Oncology, Faculty of Medicine, University of Alexandria

Abstract

Introduction: Head and neck cancer is a terminology used for a group of cancers originating in the lips, oral cavity, oropharynx, salivary glands, larynx, pharynx, hypopharynx, nasopharynx, and sinuses. These cancers represent a significant global health burden, accounting for substantial morbidity and mortality. These malignancies, often linked to complex etiologies, pose diagnostic and therapeutic challenges, with recurrence rates and survival outcomes varying widely. Understanding recurrence patterns and their impact is crucial for optimizing management strategies. So, we aimed of determine the pattern of failure for non-metastatic head and neck squamous cell carcinomas (SCC), the prognostic and predictive factors for recurrence of head and neck squamous cell carcinoma (HNSCC), local failure free survival (LFFS), distant failure free survival (DFFS), disease-free survival (DFS) and overall survival.
AIM OF THE WORK
The aim of this study was to identify the failure pattern associated with non-metastatic squamous cell carcinomas (SCC) of the head and neck.
To identify risk factors for recurrence of head and neck SCC and methods for preventing it.

Keywords