URINARY VITAMIN D-BINDING PROTEIN AS A MARKER OF OVARIAN RESERVE

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of Obstetrics & Gynaecology, Faculty of Medicine, University of Alexandria.

2 Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University, Egypt

3 Department of Obstetrics and Gynecology, Faculty of Medicine

4 Department of Clinical & chemical Patholohy**, Faculty of Medicine, Alexandria University, Egypt

Abstract

Ovarian reserve traditionally refers to the store of eggs a woman has in her ovaries that have the potential to produce mature follicles for ovulation to sustain the menstrual cycle and/or create a pregnancy. Several predictors of ovarian reserve have been identified, including patient age, basal levels of FSH, AMH, and AFC.

AIM OF THE WORK:
The aim of this study was to detect the predictive value of urinary vitamin D-binding protein as a marker of ovarian reserve.

PATIENTS AND METHODS:
The study was conducted on 150 females in the fertile age group (20-37 years) after approval of the local ethical committee. A written informed consent was obtained from every female included in the study. Females were classified based on the preliminary measurement of AMH into 50 patients with high AMH suggested to be PCOS, 50 patients with low AMH suggested to be poor ovarian reserve and 50 females with normal AMH as a control group.
Inclusion criteria:
1- 50 patients with polycystic ovary syndrome (PCOS).
2- 50 patients with diminished ovarian reserve.
3- 50 normal control (NC) participants.

Keywords