EVALUATION OF THE RELATION BETWEEN THE BLOOD SUGAR LEVEL AND THE INTRAOCULAR PRESSURE IN DIABETIC PATIENTS

Document Type : Preliminary preprint short reports of original research

Authors

1 Ophthalmology department, faculty of medicine, Alexandria University, Alexandria, Egypt

2 Department of Ophthalmology, Faculty of Medicine, Alexandria University

Abstract

Glaucoma is one of the main causes of irreversible but potentially preventable vision loss, which is described as a group of multifactorial ocular disorders with a clinically distinctive optic neuropathy and potentially progressive changes at the optic nerve head (ONH). It is the second most common cause of blindness after cataract, making it a serious public health concern. Primary open angle glaucoma(POAG) is the most common type affecting approximately 57.5 million people worldwide, with a prevalence of 2% to 4% of individuals aged 40 and older and about 10% of those aged 75 and older.
Diabetes Mellitus (DM) is one of the most prevalent metabolic diseases primarily characterized by hyperglycemia associated with changes in the metabolism of fat, protein and carbohydrates. Several common mechanisms have been proposed to contribute to the possible relationship between glaucoma and diabetes. For example , Results showed a two- to threefold increase in aqueous humor glucose levels in diabetic rats compared to those of non-diabetic control rats. Elevated glucose levels in aqueous humor of diabetic patients may induce increased ECM accumulation in the trabecular meshwork contributing to resistance in aqueous outflow and elevated IOP.

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ALEXMED ePosters
Volume 6, Issue 4
September 2024
Pages 92-93

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