EVALUATION OF FETAL MYOCARDIAL PERFORMANCE INDEX IN EARLY- AND LATE-ONSET PRE-ECLAMPSIA

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University

2 Obstetric and Gynecology department, faculty of Medicine, Alexandria University, Alexandria

3 Department of Obstetrics & Gynaecology, Faculty of Medicine, University of Alexandria.

4 Department of Obstetrics & Gynaecology, Faculty of Medicine, University of Alexandria.

Abstract

Preeclampsia ranks as one of the leading causes of maternal mortality, significant maternal morbidity, and negative neonatal outcomes worldwide. Placental-mediated disease including preeclampsia originates from a particular pathophysiological event in the first trimester associated with placental maladaptation and inadequate vascular remodeling of the spiral arterioles. Impaired trophoblastic invasion of maternal spiral arteries in cases of preeclampsia increases vascular resistance in uteroplacental circulation and may affect fetal cardiac function by causing increased cardiacafterload. The myocardial performance index is a doppler index of combined systolic and diastolic ventricular myocardial performance. It has been proposed as a potential useful predictor of global cardiac function.

AIM OF THE WORK
The aim of this study was to evaluate the myocardial performance index of the left side of the fetal heart in early- and late- onset pre-eclampsia and to compare it with normotensive pregnancies.

PATIENTS AND METHODS
This case control study was conducted on 60 pregnant women with gestational age: 28-40 weeks, 30 of them were cases (preeclamptic group) and 30 were controls (normotensive group), the preeclamptic group was further subdivided into early onset preeclamptic subgroup (20 cases) (8 of them were IUGR while 12 of them were not IUGR) and late onset preeclamptic subgroup (10 cases) (All of them were not IUGR).

Keywords