COMPARATIVE STUDY BETWEEN ANTI-INCONTINENCE PESSARY AND IMIPRAMINE IN TREATMENT OF STRESS INCONTINENCE

Document Type : Preliminary preprint short reports of original research

Authors

1 Obstetrics and Gynecology Department, Faculty of Medicine, Alexandria University

2 Obstetrics and Gynecology Department, Faculty of Medicine, Alexandria University, Egypt

3 Obstetric and Gynecology department, faculty of Medicine, Alexandria University, Alexandria

4 Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University

Abstract

Stress urinary incontinence (SUI) is defined as involuntary urine leakage resulting from increased intra-abdominal pressure.
Risk Factors for Urinary Incontinence
Multiple risk factors may predispose a woman to urinary incontinence. Risks factors such as age, race/ethnicity, pregnancy/delivery, family history, physical activity, smoking, and obesity are commonly implicated. Urinary incontinence is also associated with pelvic floor disorders including prolapse, irritable bowel syndrome and prior pelvic surgery including hysterectomy.
The female continence mechanism involves three distinct components: the internal urethral sphincter, the external urethral sphincter, and appropriate proximal urethral support. All three aspects must be present to prevent SUI
Treatment Options
The typical approach to treatment of SUI is a stepped care plan that starts with noninvasive behavioral modifications followed by devices and pharmacologic interventions. Surgery is the final step for women having symptoms that do not respond to initial treatment.
Incontinence pessaries are silicone or rubber devices that are placed transvaginally. They are designed to support the urethra and bladder wall, increase urethral length, and provide gentle compression of the urethra against the pubic bone. Pessaryreduces and often prevents leakage when intra-abdominal pressure increases. From this position, an incontinence pessary supports the urethrovesical junction in the same way a vaginal sling implanted surgically.
Imipramine is a tertiary amine tricyclic antidepressant, improve stress urinary incontinence by decreasing the contractility of bladder and increasing the urethral outlet resistance.

Keywords

ALEXMED ePosters
Volume 6, Issue 4
September 2024
Pages 39-40

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