ROLE OF DIFFUSION WEIGHTED IMAGING MRI IN THE EVALUATION OF GRAVES’ ORBITOPATHY

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of Radiodiagnosis, Faculty of medicine, Alexandria university, Alexandria, Egypt

2 Department of Ophthalmology, Faculty of Medicine, Alexandria University

3 Department of Radiodiagnosis, Faculty of Medicine, University of Alexandria

4 Department of Radiodiagnosis and Intervention, Faculty of Medicine, Alexandria University

Abstract

Graves' orbitopathy (GO) is a most serious extra-thyroidal manifestations of Graves' disease. It typically follows a predictable biphasic course: an initial active phase lasting 6-18 months, followed by an inactive phase characterized by fibrosis and fatty infiltration. The Clinical Activity Score (CAS) is commonly used to assess disease activity; however, it is limited to the visible anterior segment of the orbit, and it may not detect potentially sight-threatening dysthyroid optic neuropathy in cases with low scores. Various imaging modalities such as computed tomography, magnetic resonance imaging, ultrasound, and colour doppler imaging are utilized to diagnose and monitor the activity of Graves' orbitopathy. Among these, MRI with Diffusion-Weighted Imaging (DWI) is emerging as a valuable non-invasive tool for evaluating disease activity and predicting treatment response. Non-EPI-DWI, in particular, offers notable advantages over echo-planar DWI, including improved resolution due to thinner-section images and the use of refocusing pulses for each recorded EPI-DWI sequence, which help to minimize distortions and artifacts at the air-bone interface.

AIM OF THE WORK:
The aim of this study was to explore the diagnostic potential of Non-EPI-DWI of the orbits in Graves' disease.

Keywords

ALEXMED ePosters
Volume 6, Issue 4
September 2024
Pages 35-36

Files

Share

How to cite

Statistics