ROLE OF DOUBLE INVERSION RECOVERY IN DETECTING LESIONS OF OPTIC NERVE IN DEMYELINATING DISEASES

Document Type : Preliminary preprint short reports of original research

Authors

1 Radiodiagnosis and Intervention, Medicine, Alexandria, Alexandria, Egypt

2 Department of Radiodiagnosis and Intervention,Faculty of Medicine, University of Alexandria

3 Department of radiodiagnosis and intervention faculty of medicine alexandria university

4 Department of neuropsychiatry, Faculty of Medicine, Alexandria University

5 Department of Radiodiagnosis and intervention, Faculty of Medicine, Alexandria University

Abstract

Introduction
Demyelinating diseases are those that lead to a loss of myelin, the sheaths of fatty tissue that surround and protect nerves so that they can send signals efficiently. A loss of myelin can cause neurological deficits, such as vision changes, weakness, altered sensation, and behavioral or cognitive (thinking) problems.
When there is a deficiency or a sudden decrease in myelin, the nerves may become damaged and have difficulty sending signals, resulting in symptoms.
Optic nerve affection in multiple sclerosis results in optic neuritis characterized clinically by some temporary loss of vision in the affected eye, usually lasting for days to weeks, color blindness, eye pain, which is usually worse when moving the eye, and flashes of light when moving the eye.
Radiologically, MRI is the modality of choice for visualizing the optic nerve by detecting hyperintense signal in optic nerve. Functional MRI or multifocal visual evoked potentials have also been shown to allow early diagnosis.

The aim of this study is to assess the role of DIR- MRI in detecting optic nerve lesions in demyelinating diseases.

Keywords