CORRELATION BETWEEN VITREORETINAL INTERFACE ABNORMALITIES AND CHANGES IN THE OUTER RETINAL LAYERS IN DIABETIC MACULAR EDEMA BY OPTICAL COHERENCE TOMOGRAPHY

Document Type : Preliminary preprint short reports of original research

Authors

1 Ophthalmology department, faculty of medicine, Alexandria University, Alexandria, Egypt

2 ophthalmology department Alexandria university

3 Department of Ophthalmology, Faculty of Medicine, University of Alexandria

Abstract

Macular edema is a common complication that threatens vision in diabetic retinopathy patients, especially those with type 1 DM, long duration of diabetes and high levels of glycosylated haemoglobin.
It has been proven that the retinal-blood barrier disruption is the main factor in macular edema pathogenesis, leading to extracellular leakage of proteins and other substances followed by accumulation of extracellular fluid and formation of macular edema.
In the present era of anti-VEGF therapy, OCT became a reliable and valuable method not only for diagnosis of DME but also for treatment protocols of DME patients. Rather than measurements of thickness, OCT can detect different structural changes in retinal layers such as formation of cystic spaces, structural integrity of outer retinal layers, accumulation of subretinal fluid, and vitreomacular interface abnormalities.

AIM:
This prospective observasional study aimed to correlate the presence of vitreo-retinal interface abnormalities with the changes occurred in the outer retinal layers by OCT scans in eyes with diabetic macular edema.

Keywords