METFORMIN PLUS MYOINOSITOL VERSUS METFORMIN IN POLYCYSTIC OVARIAN SYNDROME WOMEN UNDERGOING OVULATIONIN DUCTION WITH LETROZOLE

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of Obstetrics and Gynecology, Faculty of Medicine- Alexandria University.

2 Department of Obstetrics and Gynecology, Faculty of Medicine

3 Department of Obstetrics and Gynecology, Faculty of Medicine, University of Alexandria

Abstract

PCOS is a syndromic disease presents in women in a myriad of ways, a spectrum of clinical signs and symptoms. Clinical or biochemical hyperandrogenism, oligo- an ovulation and polycystic morphology are the generally accepted diagnostic criteria.
Those women have an increased risk of metabolic and reproductive disorders, such as type 2 diabetes mellitus, obesity and dyslipidemia. Oligo/an ovulatory women without clinical or bio- chemical evidence of hyperandrogenism tend to be the least affected by the sequela of PCOS, so the accurately diagnosing women may assist clinicians in predicting life-long risks and interventions to patients on a more individualized basis.
Assessing the effect of combined metformin and myo-inositol as compared to metformin alone in terms of ovarian response of infertile PCOS women undergoing ovulation induction cycles is the main scope of this study.

AIM OF THE WORK:
The aim of this work was to assess the effect of combined metformin and myo-inositol as compared to metformin alone in terms of ovarian response and improvement in insulin resistance parameters in infertile PCOS women undergoing ovulation induction cycles.

Keywords