COMPARATIVE STUDY BETWEEN PLATELETS RICH PLASMA AND CORTICOSTEROID LOCAL INJECTIONS IN CHRONIC LATERAL HUMERAL EPICONDYLITIS

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of Orthopaedic Surgery and Traumatology, Faculty of Medicine, University of Alexandria

2 Department of Orthopedic Surgery and Traumatology, Faculty of Medicine, Alexandria University

Abstract

INTRODUCTION:
Lateral epicondylitis is the most commonly diagnosed condition of the elbow and affects approximately 1% to 3% of the population. It is the most common overuse syndrome which related to excessive wrist extension and commonly referred to as “tennis elbow,” but it is actually more common in non-tennis players. The condition mostly occurs in patients whose activities require strong gripping or repetitive wrist movements. Individuals between the ages of 35 and 50 years are at high risk. The dominant arm is most frequently affected.
The cause of lateral epicondylitis is unknown. It is thought that lesions occur in the common origin of the wrist and finger extensors on the lateral epicondyle because of a combination of mechanical overloading and abnormal microvascular responses in the form of Angio fibroblastic degeneration and collagen disarray. Light microscopy reveals both an excess of fibroblasts and blood vessels that are consistent with neo vessels or angiogenesis.
Platelet-rich plasma (PRP) is promoted as an ideal biologic autologous blood-derived product. It can be exogenously applied to various tissues where, upon platelet activation, a release of high concentrations of platelet derived growth factors occurs.
Platelet-rich plasma applications enhance wound healing, bone healing, and also tendon healing. In addition, PRP also possesses antimicrobial properties that may contribute to the prevention of infections.

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