Morsy, E., Sabry, A., Alkafafy, A., Guirguis Baskharon, M., Aiad, A. (2024). FACTORS AFFECTING TIME TO RECOVERY FROM DIABETIC KETOACIDOSIS IN ADULT DIABETIC PATIENTS IN ALEXANDRIA MAIN UNIVERSITY HOSPITAL. ALEXMED ePosters, 6(3), 53-54. doi: 10.21608/alexpo.2024.313989.1928
Eman Youssef Morsy; Ahmed Aabdelfatah Sabry; Asmaa Mohamed Alkafafy; Mina Guirguis Baskharon; Ahmed Abdelmajeed Aiad. "FACTORS AFFECTING TIME TO RECOVERY FROM DIABETIC KETOACIDOSIS IN ADULT DIABETIC PATIENTS IN ALEXANDRIA MAIN UNIVERSITY HOSPITAL". ALEXMED ePosters, 6, 3, 2024, 53-54. doi: 10.21608/alexpo.2024.313989.1928
Morsy, E., Sabry, A., Alkafafy, A., Guirguis Baskharon, M., Aiad, A. (2024). 'FACTORS AFFECTING TIME TO RECOVERY FROM DIABETIC KETOACIDOSIS IN ADULT DIABETIC PATIENTS IN ALEXANDRIA MAIN UNIVERSITY HOSPITAL', ALEXMED ePosters, 6(3), pp. 53-54. doi: 10.21608/alexpo.2024.313989.1928
Morsy, E., Sabry, A., Alkafafy, A., Guirguis Baskharon, M., Aiad, A. FACTORS AFFECTING TIME TO RECOVERY FROM DIABETIC KETOACIDOSIS IN ADULT DIABETIC PATIENTS IN ALEXANDRIA MAIN UNIVERSITY HOSPITAL. ALEXMED ePosters, 2024; 6(3): 53-54. doi: 10.21608/alexpo.2024.313989.1928
FACTORS AFFECTING TIME TO RECOVERY FROM DIABETIC KETOACIDOSIS IN ADULT DIABETIC PATIENTS IN ALEXANDRIA MAIN UNIVERSITY HOSPITAL
1Department of Internal Medicine, Faculty of Medicine, University of Alexandria
2Department of Surgery , faculty of medicine , Alexandria university
3Department of Emergency Medicine Faculty of Medicine Alexandria University
4Department of Emergency Medicine3, Faculty of Medicine, Alexandria University
5Department of Emergency Medicine, Faculty of Medicine, Alexandria University
Abstract
Diabetic ketoacidosis (DKA) represents a critical metabolic consequence of absolute or relative insulin deficiency in DM. This deficiency disrupts glucose utilization, promoting lipolysis and formation of ketone bodies as alternative fuel,this uncontrolled ketogenesis leads to ketonemia and metabolic acidosis. DKA diagnosis and classification depend on American Diabetes Association (ADA) criteria:blood glucose > 200 mg/dl, arterial pH < 7.3, bicarbonate ≤ 18 mEq/L, presence of ketonemia or ketonuria. Missed insulin doses and infections are the most common precipitating factors. Early symptoms include nausea, vomiting, polyuria, and polydipsia. Progression to Kussmaul breathing, dehydration signs, and coma can occur if untreated. DKA may be the initial presentation in undiagnosed DM. Management necessitates ICU admission within the first 24-48 hours for fluid resuscitation, insulin therapy, electrolytes correction, correctionof acid-base abnormalities, and treating the precipitating factor. Prompt diagnosis and early intervention are crucial to prevent significant morbidity and mortality associated with DKA.
Aim of the work: The aim of this study was to identify the factors affecting time of recovery from DKA in adult diabetic patients including patient related factors (e.g. age, severity of illness, electrolyte imbalance, time of presentation) and treatment related factors (e.g., type and timing of insulin therapy, fluid management, electrolyte replacement).
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