COMPARING DIFFERENT DOSE REGIMENS OF ORAL IRON SUPPLEMENTATION FOR MANAGEMENT OF IRON DEFICIENCY ANEMIA DURING PREGNANCY

Document Type : Preliminary preprint short reports of original research

Authors

1 Alexandria university obstetric&gynecology

2 Department of Obstetrics and Gynecology, Faculty of Medicine, University of Alexandria

3 Department of Obstetrics and Gynecology, Faculty of Medicine, University of Alexandria.

Abstract

During pregnancy there is disproportionate increase in plasma volume up to 50%, RBC 33% and Hb 18-20% mass. In addition, there is marked demand of extra iron during pregnancy especially in the second half of pregnancy.Iron deficiency anemia is microcytic hypochromic anemia and is most common type of anemia during pregnancy. Causes of Iron deficiency anemia: Nutritional causes (60%), dimorphic anemia (due to deficiency iron and folic acid), Hemolytic anemia hemoglobinopathies. Anemia due to blood loss: Acute: Antepartum hemorrhage, postpartum hemorrhage and Chronic example bleeding per rectum. During pregnancy routine investigations are done to diagnose iron deficiency anemia: CBC, serum iron, serum ferritin, TIBC, serum transferrin level.Serum ferritin is the best single indicator of storage iron provided a cut-off point of 30 mg/l is used, sensitivity of 90%, and specificity 85%. Guidelines for iron deficiency anemia are different according to multiple factors that determine the regimen for management.

AIM:
The aim of this study was to compare different dose regimens of iron supplements for management of moderate iron deficiency anemia during pregnancy.

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