FAMILIAL HYPERCHOLESTEROLEMIA INCIDENCE AMONG CORONARY ARTERY DISEASE PATIENTS IN THE EGYPTIANS AND THE APPLICABILITY OF DUTCH DIAGNOSTIC CRITERIA

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of Cardiology and Angiology, Faculty of Medicine, Alexandria University, Egypt.

2 Department of Cardiology and Angiology Medical Research Institute , Alexandria university

3 Department of Cardiology and Angiology Faculty of Medicine

4 Department of cardiology and angiology faculty of medicine Alexandria university

Abstract

Familial hypercholesterolemia (FH) is a hereditary lipoprotein metabolic anomaly characterized by raised blood levels of low-density lipoprotein (LDL) cholesterol and an increased risk of developing early cardiovascular diseases. Clinical features, family history, elevated LDL-cholesterol values, and more recently, genetic testing, are the cornerstones for the diagnosis. Treatment and early diagnosis are essential. Since elevated levels of low-density lipoprotein (LDL) cholesterol are the primary cause of atherosclerosis. Novel drugs, LDL apheresis, and other experimental therapy can be used in some subgroups of FH patients, improving their prognosis. The cornerstone of treatment for this illness is the use of statins. This review attempts to demonstrate how common FH is among CVD patients as opposed to normal people in our community and the applicability of Dutch diagnostic criteria in these patients
AIM OF THE WORK:
The aim of this study was to assess the incidence of FH among patients
with coronary heart disease and the applicability Dutch diagnostic criteria in these patients.

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