SUBCLINICAL LEFT VENTRICULAR DYSFUNCTION IN ‎ASYMPTOMATIC DIABETIC PATIENTS ASSESSED BY TWO-‎DIMENSIONAL SPECKLE TRACKING ECHOCARDIOGRAPHY

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of Cardiology and Angiology ,Faculty of Medicine, Alexandria ‎University

2 Department of Cardiology and Angiology ,Faculty of Medicine, Alexandria ‎University

Abstract

Introduction: Diabetes mellitus‏ ‏‎(DM) is the most common endocrinological disease in ‎the world and its presence predicts an increased risk for development of cardiovascular ‎disease, heart failure and death. Diabetic cardiomyopathy is currently defined as a ‎diastolic dysfunction, and several studies of DM patients have identified left ventricle ‎‎(LV) diastolic dysfunction as the earliest functional alteration in the course of diabetic ‎cardiomyopathy. Several studies have identified tissue Doppler imaging (TDI) as a ‎sensitive technique for the evaluation of diastolic and systolic myocardial dysfunction ‎in diabetic patients even in the presence of normal cardiac function in conventional ‎echocardiography. Echocardiographic techniques such 2D speckle tracking global ‎longitudinal strain analysis permits early identification of LV systolic dysfunction ‎despite preserved LV ejection fraction. It is a type of strain imaging and has advantage ‎of calculating myocardial strain independent of angle of incidence. There is growing ‎evidence that this modality provides cumulative information in the clinical setting.‎

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