EVALUATION OF TREATMENT MODALITIES OF FUSARIUM FUNGAL KERATITIS

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of ophthalmology, faculty of medicine, Alexandria university, Alexandria ,Egypt

2 Department of Microbiology, Faculty of Medicine, University of Alexandria

3 Department of Ophthalmology, Faculty of Medicine, University of Alexandria

Abstract

Infection of the cornea by filamentous fungus and yeasts, often known as keratomycosis or fungal keratitis, is common. This illness may pose a harm to the eyes. The prevalence of different causes varies according on where people are from. The weather is also a major role. Filamentous fungi are more common in tropical and subtropical areas, whereas yeasts are thought to predominate in temperate zones.
The most common individual risk factors for FK include trauma, immunes uppression, ocular surface disease, and contact lens usage, any or all of which might increase susceptibility to a fungal infection
A fungal infection as a cause of keratitis may be difficult to identify clinically, and delays in diagnosis are frequent due to negative or delayed culture findings
Topical anti-fungal medicines are the mainstay of pharmacological therapy for fungal keratitis. No antifungal recommendations based on individual fungal isolation are presently available. Many of these anti-fungal treatments have varying degrees of corneal penetration activity or efficacy. The most effective method of therapy is still the use of pharmacologically active antimicrobials via a topical application. Intra-stromal injections have been controversial since they have not been found to be more effective than topical instillation.

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