THE PREVALENCE OF FUCHS ENDOTHELIAL CORNEAL DYSTROPHY IN ADULT PATIENTS SCHEDULED FOR CATARACT SURGERY .

Document Type : Preliminary preprint short reports of original research

Authors

1 Ophthalmology department, faculty of medicine, Alexandria University, Alexandria, Egypt

2 Department of Ophthalmology, Faculty of Medicine, Alexandria University

Abstract

Introduction:
Fuchs endothelial dystrophy (FECD) is a corneal endothelial disease characterized clinically by corneal endothelial dysfunction and guttae excrescences on the posterior corneal surface. FECD is characterized by dysfunctional corneal endothelium that deposits a posterior collagenous layer between the Descemet's membrane and the endothelial monolayer. In a healthy cornea, stromal hydration is maintained by the delicate balance between passive, inward diffusion of aqueous and active, outward transport of excess fluids by endothelium. FECD leads to impairment of the endothelial pump mechanism, resulting in corneal edema and its clinical sequelae.
Clinical manifestations of FECD may range from mild to severe. In mild FECD, patients are asymptomatic with no impairment of vision, and a diagnosis is most commonly made by incidental observations of corneal guttae during routine ophthalmologic examinations. In severe FECD, marked dysfunction of central endothelium with dense accumulations of central guttae, result in significant corneal edema, scarring and impairment of visual function.

Keywords

ALEXMED ePosters
Volume 5, Issue 1
January 2023
Pages 24-25

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