ElGoweini, H., Bayoumi, N., Goweida, M., Zohair, H. (2023). THE PREVALENCE OF FUCHS ENDOTHELIAL CORNEAL DYSTROPHY IN ADULT PATIENTS SCHEDULED FOR CATARACT SURGERY .. ALEXMED ePosters, 5(1), 24-25. doi: 10.21608/alexpo.2023.194281.1563
Hesham Fouad ElGoweini; Nader Hussein Bayoumi; Mohamed Bahgat Goweida; Haitham Mohamed Farag Zohair. "THE PREVALENCE OF FUCHS ENDOTHELIAL CORNEAL DYSTROPHY IN ADULT PATIENTS SCHEDULED FOR CATARACT SURGERY .". ALEXMED ePosters, 5, 1, 2023, 24-25. doi: 10.21608/alexpo.2023.194281.1563
ElGoweini, H., Bayoumi, N., Goweida, M., Zohair, H. (2023). 'THE PREVALENCE OF FUCHS ENDOTHELIAL CORNEAL DYSTROPHY IN ADULT PATIENTS SCHEDULED FOR CATARACT SURGERY .', ALEXMED ePosters, 5(1), pp. 24-25. doi: 10.21608/alexpo.2023.194281.1563
ElGoweini, H., Bayoumi, N., Goweida, M., Zohair, H. THE PREVALENCE OF FUCHS ENDOTHELIAL CORNEAL DYSTROPHY IN ADULT PATIENTS SCHEDULED FOR CATARACT SURGERY .. ALEXMED ePosters, 2023; 5(1): 24-25. doi: 10.21608/alexpo.2023.194281.1563
THE PREVALENCE OF FUCHS ENDOTHELIAL CORNEAL DYSTROPHY IN ADULT PATIENTS SCHEDULED FOR CATARACT SURGERY .
1Ophthalmology department, faculty of medicine, Alexandria University, Alexandria, Egypt
2Department of Ophthalmology, Faculty of Medicine, Alexandria University
Abstract
Introduction: Fuchs endothelial dystrophy (FECD) is a corneal endothelial disease characterized clinically by corneal endothelial dysfunction and guttae excrescences on the posterior corneal surface. FECD is characterized by dysfunctional corneal endothelium that deposits a posterior collagenous layer between the Descemet's membrane and the endothelial monolayer. In a healthy cornea, stromal hydration is maintained by the delicate balance between passive, inward diffusion of aqueous and active, outward transport of excess fluids by endothelium. FECD leads to impairment of the endothelial pump mechanism, resulting in corneal edema and its clinical sequelae. Clinical manifestations of FECD may range from mild to severe. In mild FECD, patients are asymptomatic with no impairment of vision, and a diagnosis is most commonly made by incidental observations of corneal guttae during routine ophthalmologic examinations. In severe FECD, marked dysfunction of central endothelium with dense accumulations of central guttae, result in significant corneal edema, scarring and impairment of visual function.