Darwish, E., Elkassar, Y., Taher, E., Loutfy, E. (2023). RELATIONSHIP BETWEEN SERUM PROGESTERONE LEVEL ON DAY OF THAWED EMBRYO TRANSFER AND PREGNANCY RATE. ALEXMED ePosters, 5(1), 6-7. doi: 10.21608/alexpo.2023.184955.1541
Emad Darwish; Yasser Elkassar; Engy Taher; Engy Islam Loutfy. "RELATIONSHIP BETWEEN SERUM PROGESTERONE LEVEL ON DAY OF THAWED EMBRYO TRANSFER AND PREGNANCY RATE". ALEXMED ePosters, 5, 1, 2023, 6-7. doi: 10.21608/alexpo.2023.184955.1541
Darwish, E., Elkassar, Y., Taher, E., Loutfy, E. (2023). 'RELATIONSHIP BETWEEN SERUM PROGESTERONE LEVEL ON DAY OF THAWED EMBRYO TRANSFER AND PREGNANCY RATE', ALEXMED ePosters, 5(1), pp. 6-7. doi: 10.21608/alexpo.2023.184955.1541
Darwish, E., Elkassar, Y., Taher, E., Loutfy, E. RELATIONSHIP BETWEEN SERUM PROGESTERONE LEVEL ON DAY OF THAWED EMBRYO TRANSFER AND PREGNANCY RATE. ALEXMED ePosters, 2023; 5(1): 6-7. doi: 10.21608/alexpo.2023.184955.1541
RELATIONSHIP BETWEEN SERUM PROGESTERONE LEVEL ON DAY OF THAWED EMBRYO TRANSFER AND PREGNANCY RATE
1Obstetrics and Gynecology Department, Faculty of Medicine, Alexandria University
2Alexandria university obstetric&gynecology
Abstract
Embryo cryopreservation and frozen-thawed embryo transfer refers to the procedures whereby embryos are cryopreserved for storage, to be thawed and transferred at a later stage after the conclusion of the stimulated cycle. Frozen-thawed embryo transfer has become a routine ART practice and the proportion of frozen-thawed embryo transfer among embryo transfer cycles has increased worldwide. Progesterone plays a vital role in both conception and the maintenance of pregnancy; as such, it has been a central focus of investigation aimed at optimizing hormonal replacement therapy. The beginning of P administration is critical. Starting too soon could lead to prematureluteinizationandstartingtoolatecouldincreaseuterinecontractility, which is negatively related to P quantity and increased uterine contractions on the day of embryotransfer leading to lower implantation rates Ideally, progesterone (p4) monitoring would be tailored to the administration method; however, given the significant practical difficulties in obtaining endometrial progesterone levels, serum P4 concentrations continue to be the mainstay marker for P4 monitoring.