CORRELATION BETWEEN DIAGNOSTIC MARKERS OF METABOLIC SYNDROME & MATERNAL VISCERAL FAT THICKNESS AND RISK OF GESTATIONAL DIABETES

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of Obstetrics & Gynecology, Faculty of Medicine, Alexandria University, Egypt

2 Department of Obstetrics and Gynaecology , Faculty of Medicine, University of Alexandria, Egypt

3 Department of Obstetrics & Gynecology, Faculty of Medicine, Alexandria University, Egypt

4 Department of Clinical & chemical Patholohy**, Faculty of Medicine, Alexandria University, Egypt

5 Department of Internal Medicine, Faculty of Medicine, University of Alexandria

Abstract

• Gestational diabetes mellitus (GDM) is the most common metabolic disorder in pregnant women. Gestational diabetes mellitus (GDM) is defined as any degree of abnormal glucose tolerance that occurs for the first-time during pregnancy and usually disappears after giving birth. It is associated with an increased risk of perinatal mortality and morbidity.
• Metabolic syndrome (MetS) is a clustering of clinical and laboratory abnormalities that include central obesity, insulin resistance, hypertension, hyperglycemia, and dyslipidemia (elevated triglycerides and reduced HDL cholesterol levels).
• It has been postulated that women with MetS are already in a state of pro inflammation and insulin resistance; therefore, it is possible that when they become pregnant, they are more susceptible to developing GDM.
Aim of the work:
The aim of this work was to assess the role of metabolic syndrome diagnostic markers and maternal visceral fat thickness in the prediction of gestational diabetes mellitus.
Patients and Methods:
Patients
• This prospective cohort study was conducted on 150 singleton pregnant women between 24th and 28th weeks of gestation attending the antenatal clinic at El-Shatby maternity university hospital and undergoing their screening for GDM.

Keywords