HASHIMOTO’S THYROIDITIS AS A RISK FACTOR OF COMPLICATIONS OF TOTAL THYROIDECTOMY.

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of Surgery, Faculty of Medicine, Alexandria University

2 Head and Neck and Endocrine Unit, Surgery Department, Faculty of Medicine, Alexandria University

3 Head and Neck and Endocrine unit, Surgery department, Faculty of medicine, Alexandria university

Abstract

Thyroid diseases are one of the most prevalent endocrinopathies globally. Most of the thyroid diseases treated surgically especially when medical treatment fails, cosmetic purposes or when thyroid cancer is suspected. Hashimoto's thyroiditis (HT), a type of chronic lymphocytic thyroiditis, is the most common autoimmune thyroid condition. Histologically, the disease is characterized by an extensive lymphocytic infiltrate in the thyroid and follicular atrophy with increased fibrosis.The diagnosis is primarily made on the basis of serum autoantibodies against thyroperoxidase and/or thyroglobulin, which may precede clinical symptoms and biochemical hypothyroidism by several years. Medical treatment is usually opted for majority of patients with Hashimoto's thyroiditis (HT). This includes both hypothyroid and hyperthyroid patients. In order to reduce thyroid volume and supplement thyroid hormone, patients with HT are typically treated conservatively with levothyroxine (L-T4) therapy. However, there are some cases where patients with HT are referred for surgery. Patients with HT, the thyroid gland tends to adhere more to its anatomical surroundings, which can increase the risk of damaging structures adjacent to the thyroid such as the parathyroid glands and the recurrent laryngeal nerve.

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