RETROSPECTIVE STUDY OF ABDOMINOPELVIC COMPUTED TOMOGRAPHIC FINDINGS IN ADVANCED BREAST CANCER PATIENTS ATTENDING SPECIALIZED ONCOLOGY CENTERS IN ALEXANDRIA

Document Type : Preliminary preprint short reports of original research

Authors

1 Department of Radio-Diagnosis , Faculty of Medicine , Alexandria University , Egypt.

2 Department of Radiodiagnosis, Faculty of Medicine, University of Alexandria.

3 Department of Radiodiagnosis, Medical Research Institute, Alexandria University

4 Department of Cancer Management and Research, Medical Research Institute, Alexandria University

5 Department of Radiodiagnosis, Faculty of Medicine ,Alexandria University

Abstract

Introduction
Although the recognition and treatment of breast cancer metastases to sites such as bone, liver, lungs, and brain are well-documented, abdominopelvic metastases of breast cancer represent a clinical challenge. Abdominopelvic Computed Tomography for breast cancer patients has been used for disease staging to detect denovo metastasis and during disease follow up to detect relapsed metastasis. Yet, in practice, its role was limited to detecting common sites for secondaries which are bone and typical hepatic metastasis. However, there are other unusual sites and patterns that are equally important and often overlooked which results in delay in the proper diagnosis. These include spleen, pseudocirrhosis of the liver, retroperitoneal involvement, soft tissues and transcoelomic spread sites. Other abdominopelvic radiographic findings are related to chemotherapy and hormonal therapy. These include: Steatohepatosis, neutropenic enterocolitis, vascular thrombotic events and uterine abnormalities. Detecting any of these unusual sites as well as any of the chemotherapy and hormonal therapy induced changes results in tailoring the treatment strategy in breast cancer patients.


Aim of the work
To examine the utility of contrast-enhanced CT for detecting abdominopelvic radiological findings in advanced breast cancer patients.

Keywords