Home Articles List Article Information
ALEXMED ePosters
Journal Archive
Volume Volume 7 (2025)
Volume Volume 6 (2024)
Volume Volume 5 (2023)
Volume Volume 4 (2022)
Volume Volume 3 (2021)
Volume Volume 2 (2020)
Volume Volume 1 (2019)
El-Ghazzawi, I., Solaiman, A., Zaki, E., Ibrahim, A. (2023). LIGHT MICROSCOPIC STUDY OF THE EFFECT OF PLATELET RICH PLASMA ON HEPATIC FIBROSIS IN ADULT MALE ALBINO RATS. ALEXMED ePosters, 5(1), 9-10. doi: 10.21608/alexpo.2022.142744.1416
Ibtihag Fathy El-Ghazzawi; Amany Abdel-Moneam Solaiman; Eiman Ibrahim Zaki; Amira Ahmed Ibrahim. "LIGHT MICROSCOPIC STUDY OF THE EFFECT OF PLATELET RICH PLASMA ON HEPATIC FIBROSIS IN ADULT MALE ALBINO RATS". ALEXMED ePosters, 5, 1, 2023, 9-10. doi: 10.21608/alexpo.2022.142744.1416
El-Ghazzawi, I., Solaiman, A., Zaki, E., Ibrahim, A. (2023). 'LIGHT MICROSCOPIC STUDY OF THE EFFECT OF PLATELET RICH PLASMA ON HEPATIC FIBROSIS IN ADULT MALE ALBINO RATS', ALEXMED ePosters, 5(1), pp. 9-10. doi: 10.21608/alexpo.2022.142744.1416
El-Ghazzawi, I., Solaiman, A., Zaki, E., Ibrahim, A. LIGHT MICROSCOPIC STUDY OF THE EFFECT OF PLATELET RICH PLASMA ON HEPATIC FIBROSIS IN ADULT MALE ALBINO RATS. ALEXMED ePosters, 2023; 5(1): 9-10. doi: 10.21608/alexpo.2022.142744.1416

LIGHT MICROSCOPIC STUDY OF THE EFFECT OF PLATELET RICH PLASMA ON HEPATIC FIBROSIS IN ADULT MALE ALBINO RATS

Article 2, Volume 5, Issue 1, January 2023, Page 9-10  XML
Document Type: Preliminary preprint short reports of original research
DOI: 10.21608/alexpo.2022.142744.1416
View on SCiNiTO View on SCiNiTO
Authors
Ibtihag Fathy El-Ghazzawi; Amany Abdel-Moneam Solaiman; Eiman Ibrahim Zaki; Amira Ahmed Ibrahim email orcid
Department of Histology and Cell Biology, Faculty of Medicine, Alexandria University
Abstract
Liver fibrosis is one of the most common causes of mortality worldwide. Platelet rich plasma (PRP) is one of the newly emerging modalities that contributes to tissue-healing process.
Aim of the work:
To study the potential effect of platelet rich plasma on hepatic fibrosis induced by thioacetamide (TAA).
Material and Methods:
Material:
18 adult male albino rats were randomly divided into 3 groups:
Group I (control): received intraperitoneal (i.p) saline twice weekly for 7 weeks.
Group II (fibrosis): received i.p injection of TAA (200 mg/kg) twice weekly for 7 weeks.
Group III (treated): received i.p injection of TAA (200 mg/kg) twice weekly for 7 weeks and PRP starting from 4th week of TAA administration to the end of the experiment.
Methods:
• Liver fibrosis was induced by intraperitoneal injection of TAA dissolved in 0.9% normal saline in a dose of 200 mg⁄kg body weight twice a week for 7 weeks. Fifteen rats were used for the purpose of PRP preparation using double centrifugation technique.
• At the end of the experiment, all groups were sacrificed and liver was taken for light microscopic examination by H&E and trichrome stains.
Keywords
fibrosis; Liver; PRP
Supplementary Files
Statistics
Article View: 131