RETROSPECTIVE STUDY OF THE IMPACT OF NEOADJUVANT THERAPY ON SURGICAL DECISIONS IN PATIENTS WITH BREAST CANCER

Document Type : Preliminary preprint short reports of original research

Authors

1 Surgery Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt

2 Department of General Surgery, Faculty of Medicine, University of Alexandria

3 Department of Clinical Oncology, Faculty of Medicine, University of Alexandria

4 01552403570

Abstract

Breast cancer is the universal most frequently diagnosed cancer in women. Over time, evolutions in understanding the biological behavior of breast cancer as a disease has made a paradigm shift in its management from radical to more conservative treatment strategies with comparable oncological outcome, overall survival yet with better quality of life, thus, making cancer breast - when early detected - less concerning type of cancer, especially that high rates of cure is being achieved.
A multidisciplinary team approach is needed for ideal management of breast cancer aiming primarily at reduction in breast cancer mortality as well as several cosmetic and oncological advantages. Breast conservation surgery is the standard of care surgical procedure for early breast cancer patients. Neoadjuvant therapy refers to the systemic treatment of breast cancer prior to definitive surgical therapy. While all systemic therapy given for non-metastatic invasive breast cancer intended to reduce risk of distant recurrence, the drive of administering it prior to surgery is to downstage the tumor and to have information regarding treatment response.

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