Zaytoun, T., Hassan, O., Nawar, M. (2022). THE DIAGNOSTIC VALUE OF INTENSIVE CARE INFECTION SCORE IN COMPARISON TO PROCALCITONIN LEVEL AND CRP IN SEPTIC ICU PATIENT. ALEXMED ePosters, 4(1), 51-52. doi: 10.21608/alexpo.2022.128010.1387
Tayseer M. Zaytoun; Osama S. Hassan; Mohamed Osama Nawar. "THE DIAGNOSTIC VALUE OF INTENSIVE CARE INFECTION SCORE IN COMPARISON TO PROCALCITONIN LEVEL AND CRP IN SEPTIC ICU PATIENT". ALEXMED ePosters, 4, 1, 2022, 51-52. doi: 10.21608/alexpo.2022.128010.1387
Zaytoun, T., Hassan, O., Nawar, M. (2022). 'THE DIAGNOSTIC VALUE OF INTENSIVE CARE INFECTION SCORE IN COMPARISON TO PROCALCITONIN LEVEL AND CRP IN SEPTIC ICU PATIENT', ALEXMED ePosters, 4(1), pp. 51-52. doi: 10.21608/alexpo.2022.128010.1387
Zaytoun, T., Hassan, O., Nawar, M. THE DIAGNOSTIC VALUE OF INTENSIVE CARE INFECTION SCORE IN COMPARISON TO PROCALCITONIN LEVEL AND CRP IN SEPTIC ICU PATIENT. ALEXMED ePosters, 2022; 4(1): 51-52. doi: 10.21608/alexpo.2022.128010.1387
THE DIAGNOSTIC VALUE OF INTENSIVE CARE INFECTION SCORE IN COMPARISON TO PROCALCITONIN LEVEL AND CRP IN SEPTIC ICU PATIENT
Critical Care Medicine Department, Faculty of Medicine, University of Alexandria.
Abstract
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. In this new definition the concept of non-homeostatic host response to infection is strongly stressed while the SIRS criteria have been removed. However, the diagnosis of sepsis and evaluation of its severity is complicated by the highly variable and non-specific nature of the signs and symptoms of sepsis. From this point biomarkers have an important place in the process of early diagnosis and stratification of the severity of sepsis and can differentiate between infectious and non-infectious causes of systemic inflammatory response The intensive care infection score (ICIS) a novel score for prediction of sepsis comprised five blood-cell derived parameters that characterize the early innate immune response which are: The mean fluorescence intensity of segmented neutrophils (SNFI), difference in hemoglobin concentration between newly formed and mature red blood cells (dCHC), total segmented neutrophil count (SN), antibody secreting lymphocyte count (ASL) and immature granulocyte count (IG). A high ICIS increases the likelihood of infection when suspected and a low ICIS decreases it. This may help the clinician in ordering extra tests or starting empirical antibiotics.
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