Document Type : Preliminary preprint short reports of original research
Authors
1
Pediatric Surgery Unit, Department of Surgery,Faculty of Medicine, Alexandria University
2
Pediatric Surgery Unit, Department of Surgery,Faculty of Medicine, Alexandria University.
3
Department of Medical oncology, Faculty of Medicine, Alexandria University.
4
Pediatric Surgery unit, Department of surgery, Faculty of Medicine, Alexandria University, Alexandria, Egypt
5
Pediatric Surgery Unit, Department of Surgery, Faculty of Medicine, Alexandria University, Alexandria, Egypt
Abstract
Introduction
Wilms’ tumor is the most common pediatric renal solid malignancy, present usually as an asymptomatic abdominal mass in most cases. Other signs and symptoms include; abdominal pain, hypertension, hematuria, and fever. The incidence of Wilms’ tumor is estimated to be about 1: 10,000 worldwide. Children with Wilms’ tumor commonly have associated congenital anomalies. An abdominal CT scan is the gold standard imaging for diagnosis. Lymph node involvement significantly worsens the prognosis of Wilms’ tumor patients. Therefore, in the interest of minimizing surgical morbidity, surgeons may choose to restrict sampling of lymph nodes to those that are most safely removed, probably sufficient to ensure accurate staging and hence extensive lymph node dissection is not necessary. According to the International Society of Pediatric Oncology (SIOP) protocol, the main treatment for Wilms’ tumor is radical nephrectomy with lymph node sampling, after preoperative chemotherapy
Aim of the work:
The aim of this study is to evaluate the outcome of hilar lymph node sampling in comparison to comprehensive lymph node dissection with regards to the pathological yield of the lymph nodes post nephrectomy in patients with Wilms’ tumor.
Keywords
)
View on SCiNiTO