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Khamis, M., Helmy, M., Swelem, M., Fares, G. (2021). EVALUATION OF MATERNAL PLACENTAL GROWTH FACTOR IN SUSPECTED PRE-ECLAMPTIC WOMEN. ALEXMED ePosters, 3(4), 89-90. doi: 10.21608/alexpo.2021.106537.1313
Mohamed Yousri Khamis; Mona Wagdy Helmy; Manal Shafik Swelem; Gamal El Sayed Fares. "EVALUATION OF MATERNAL PLACENTAL GROWTH FACTOR IN SUSPECTED PRE-ECLAMPTIC WOMEN". ALEXMED ePosters, 3, 4, 2021, 89-90. doi: 10.21608/alexpo.2021.106537.1313
Khamis, M., Helmy, M., Swelem, M., Fares, G. (2021). 'EVALUATION OF MATERNAL PLACENTAL GROWTH FACTOR IN SUSPECTED PRE-ECLAMPTIC WOMEN', ALEXMED ePosters, 3(4), pp. 89-90. doi: 10.21608/alexpo.2021.106537.1313
Khamis, M., Helmy, M., Swelem, M., Fares, G. EVALUATION OF MATERNAL PLACENTAL GROWTH FACTOR IN SUSPECTED PRE-ECLAMPTIC WOMEN. ALEXMED ePosters, 2021; 3(4): 89-90. doi: 10.21608/alexpo.2021.106537.1313

EVALUATION OF MATERNAL PLACENTAL GROWTH FACTOR IN SUSPECTED PRE-ECLAMPTIC WOMEN

Article 1, Volume 3, Issue 4, December 2021, Page 89-90  XML
Document Type: Preliminary preprint short reports of original research
DOI: 10.21608/alexpo.2021.106537.1313
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Authors
Mohamed Yousri Khamis1; Mona Wagdy Helmy2; Manal Shafik Swelem3; Gamal El Sayed Fares email 4
1Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University
2Department of Clinical and Chemical Pathology, Faculty of Medicine Alexandria University
3Department of obstetrics and gynaecology, Faculty of medicine
4Department of Obstetrics and gynecology, Alexandria Faculty of Medicine, Alexandria University
Abstract
Preeclampsia, one of the hypertensive disordersof pregnancy, is a disease of vascular endothelial dysfunction occurringafter 20 weeks of gestation and can present as late as 4-6 weeks postpartum. It is clinically defined by gestational hypertension and proteinuria, with or without edema. Placental growth factor (PlGF) is a protein from the vascular endothelial growth factor (VEGF) family, which promotes angiogenesis, maintains fetal blood supply despite any maternal generalized vasoconstriction and is present in high concentration in the trophoblastic tissues. Any abnormal levels can be associated with placental insufficiency, therefore bad prognosis of preeclamptic disorders.
AIM OF THE WORK:
To assess serum level of maternal PlGF in pregnant women with high risk of developing preeclampsia and its role in prediction of secondary fetal and maternal outcomes.
SUBJECTS AND METHODS:
The study was a case series randomized study conducted on 250 pregnant females with high risk of developing preeclampsia attending antenatal care clinic in El-Shatby maternity university hospital. Women were approached individually, after being consented to be included in the study, and they were asked for blood samples to assess serum level of placental growth factor.
Keywords
Placental growth factor (PlGF); high risk preeclamptic women; fetal distress
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