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Elnagdy, S. (2021). A COMPARATIVE STUDY BETWEEN SOME THERAPEUTIC APPROACHES FOR THE TREATMENT OF POST ACNE ERYTHEMA. ALEXMED ePosters, 3(4), 27-28. doi: 10.21608/alexpo.2021.91046.1250
Sarah Abd Elmoneim Elnagdy. "A COMPARATIVE STUDY BETWEEN SOME THERAPEUTIC APPROACHES FOR THE TREATMENT OF POST ACNE ERYTHEMA". ALEXMED ePosters, 3, 4, 2021, 27-28. doi: 10.21608/alexpo.2021.91046.1250
Elnagdy, S. (2021). 'A COMPARATIVE STUDY BETWEEN SOME THERAPEUTIC APPROACHES FOR THE TREATMENT OF POST ACNE ERYTHEMA', ALEXMED ePosters, 3(4), pp. 27-28. doi: 10.21608/alexpo.2021.91046.1250
Elnagdy, S. A COMPARATIVE STUDY BETWEEN SOME THERAPEUTIC APPROACHES FOR THE TREATMENT OF POST ACNE ERYTHEMA. ALEXMED ePosters, 2021; 3(4): 27-28. doi: 10.21608/alexpo.2021.91046.1250

A COMPARATIVE STUDY BETWEEN SOME THERAPEUTIC APPROACHES FOR THE TREATMENT OF POST ACNE ERYTHEMA

Article 196, Volume 3, Issue 4, December 2021, Page 27-28  XML
Document Type: Preliminary preprint short reports of original research
DOI: 10.21608/alexpo.2021.91046.1250
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Author
Sarah Abd Elmoneim Elnagdy email
Dermatology, Venereology and Andrology, Faculty of Medicine, University of Alexandria
Abstract
Post acne erythema (PAE) is a common sequalae in many acne patients. This is due to wound healing-related dilatory changes in microvascular structures such as the microcapillary plexus in the very superficial dermis which are not detectable by the naked eye as visible telangiectasia but as general redness. Lesions appear as telangiectatic and erythematous macules which result from skin inflammation.
Oxymetazoline is a synthetic, direct acting, imidazoline type, sympathomimetic agonist with potent vasoconstricting action that is highly selective for alpha 1 adrenoreceptors and partially selective for alpha 2 adrenoreceptors. Tranexamic acid (TXA) is an antifibrinolytic agent that decrease erythema by repressing proinflammatory cytokines (IL-6 and TNFα) and angiogenesis.
Skin micro-needling is a technique that involves repeated puncturing of the skin using sterilized microneedles to create micro channels with minimal damage to the epidermis leading to the production of growth factors, which help to facilitate skin healing and repair. These micro channels also facilitate the absorption of topically applied drugs.
Keywords
Post acne erythema (PAE); Tranexamic acid (TXA); Oxymetazoline(OXZ)
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