Ebrahim, Y. (2021). ROLE OF ADVANCED MAGNETIC RESONANCE IMAGING TECHNIQUES IN DISTINCTION BETWEEN CEREBRAL ABSCESSES AND HIGH-GRADE NEOPLASMS.. ALEXMED ePosters, 3(2), 59-60. doi: 10.21608/alexpo.2021.78612.1172
Yousra mohamed Ebrahim. "ROLE OF ADVANCED MAGNETIC RESONANCE IMAGING TECHNIQUES IN DISTINCTION BETWEEN CEREBRAL ABSCESSES AND HIGH-GRADE NEOPLASMS.". ALEXMED ePosters, 3, 2, 2021, 59-60. doi: 10.21608/alexpo.2021.78612.1172
Ebrahim, Y. (2021). 'ROLE OF ADVANCED MAGNETIC RESONANCE IMAGING TECHNIQUES IN DISTINCTION BETWEEN CEREBRAL ABSCESSES AND HIGH-GRADE NEOPLASMS.', ALEXMED ePosters, 3(2), pp. 59-60. doi: 10.21608/alexpo.2021.78612.1172
Ebrahim, Y. ROLE OF ADVANCED MAGNETIC RESONANCE IMAGING TECHNIQUES IN DISTINCTION BETWEEN CEREBRAL ABSCESSES AND HIGH-GRADE NEOPLASMS.. ALEXMED ePosters, 2021; 3(2): 59-60. doi: 10.21608/alexpo.2021.78612.1172
ROLE OF ADVANCED MAGNETIC RESONANCE IMAGING TECHNIQUES IN DISTINCTION BETWEEN CEREBRAL ABSCESSES AND HIGH-GRADE NEOPLASMS.
Department of Radiodiagnosis and Intervention, Faculty of Medicine, University of Alexandria.
Abstract
• Distinguishing between cerebral abscess and rim-enhancing tumor is a problem that is encountered frequently by radiologists. Conventional contrast-enhanced MRI reveals ring enhancement of a brain abscess that is similar to the ring enhancement of a necrotic high-grade glioma or metastasis. • Advanced MRI techniques (DWI, MRS and DSC MR perfusion) may be used to differentiate between cerebral abscesses and high grade brain neoplasms. • DWI is an advanced MRI technique that provides the physiological nature of the disease based on motion of water molecules across cell membrane. • DWI allows assessment of the cellularity of the lesion non-invasively, as cellular and subcellular elements significantly impede the mobility of water molecules, thus densely cellular lesions show restricted diffusion and hence low ADC values. • Magnetic Resonance spectroscopy (MRS) is a non-invasive diagnostic test for measuring biochemical changes in the brain, it MRS is capable of differentiating normal from pathologic brain. • Dynamic susceptibility contrast (DSC) perfusion MRI is a technique that allows derivation of relative cerebral blood volume (rCBV) maps on the basis of the susceptibility effect related to passage of MRI contrast material through tissue. • It provides noninvasive physiologic measurements of tumor vascularity and relative cerebral blood volume (rCBV) maps, which can be used to identify and quantify areas of neovascularization. • We try to evaluate the role of advanced MRI techniques (DWI, MRS, DSC PERFUSION) to reach a final diagnosis in a case of brain abscess versus a cystic or necrotic tumor.
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