Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301THE ADDED VALUE OF SUSCEPTIBILITY WEIGHTED IMAGING IN NON TRAUMATIC PEDIATRIC BRAIN LESIONS1213516010.21608/alexpo.2021.55984.1099ENNagham KamalGawadDepartment of Radiology, University of AlexandriaJournal Article20201231Susceptibility‐weighted imaging (SWI) is a magnetic resonance imaging (MRI) technique that enhances image contrast by using the susceptibility differences between tissues. The strength of SWI is in its ability to identify hemorrhage, calcium and nonheme iron by virtue of its susceptibility artifact, Susceptibility weighted imaging (SWI) has become a key MR sequence in pediatric neuroimaging. <br />Aim of the work<br />The aim of this study is to identify the added value of Susceptibility Weighted Imaging (SWI) in evaluation of non-traumatic pediatric brain lesions. <br />Subjects and Methods<br />Subjects:<br />The study was conducted on 20 patients .<br />All the patients were below 18 years old from both genders and with history of non traumatic brain lesions.<br />Methods:<br />The studied patients were subjected to the following:<br />• Full detailed history taking and thorough clinical examination. <br />• MRI examination of brain including :<br /> Routine magnetic resonance imaging:<br />• T1 weighted axial sequences.<br />• T2 weighted axial sequences.<br />• Fluid-attenuated inversion-recovery (FLAIR) axial sequences.<br /> Axial susceptibility imaging (SWI)Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301COMPARATIVE STUDY BETWEEN THE EFFICACY OF INTRALESIONAL BLEOMYCIN INJECTION VERSUS MICRONEEDLING-ASSISTED TOPICAL BLEOMYCIN SPRAYING IN TREATMENT OF PLANTAR WARTS2313517910.21608/alexpo.2021.55567.1092ENShaimaa SobhyMohameddermatology and venerology, faculty of medicine, alexandria university, alexandria, egyptJournal Article20201228Plantar warts are benign epithelial tumors affecting the plantar surface of the foot. They are caused by various strains of HPV. They may cause pain and disfigurement. They mostly occur in children older than five years, adolescents and immunosuppressed patients. Treatment of plantar warts is a therapeutic challenge regarding both tolerability and efficacy.<br />Bleomycin is used for the treatment of severe types of warts. The bleomycins are a group of water-soluble glycopeptides extracted from a strain of Streptomyces verticillus with an anti-bacterial, antiviral and cytotoxic activity. Intralesional bleomycin has been reported to be a promising approach and effective treatment of resistant warts, with cure rates from 63% to 100%. The mechanism of action of bleomycin in the treatment of warts is not clear. Bleomycin has been observed to inhibit DNA and protein synthesis and hence can induce tissue death.<br />Microneedling uses fine needles to puncture the epidermis. Needling of plantar wart induces local inflammation and a subsequent cell mediated immune response against human papillomavirus. It is used also as a method of transdermal drug delivery by creation of micropores through the stratum corneum and this technique enhance the absorption of drugs like bleomycin, enhances the efficacy and decreases the period of therapy.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301EVALUATION OF EGYPTIAN CHILDREN IN THE PRIMARY STAGE USING TEST OF PROBLEM SOLVING 3 ELEMENTARY3413567510.21608/alexpo.2021.55816.1096ENMariam AshrafHabibDepartment of Otorhinolaryngology, MOHP Faculty of Medicine, University of AlexandriaJournal Article20201230The term executive functions refers to a constellation of cognitive abilities enabling and driving adaptive, goal-oriented behavior which include updating and manipulating information mentally, inhibition of what is irrelevant to current goals, anticipation, goal selection, planning and organization, initiation of activity, self-regulation and monitoring, mental flexibility, attention deployment, working memory, problem solving and feedback utilization. Such capabilities are considered ‘executive’ because they are believed to subserve a supervisory role involving the integration of information stored elsewhere in the brain, and can have the potential to affect the processing of other cognitive domains: learning, memory, language, and visual perception.<br />The components of EFs are a family of three, interrelated core skills (inhibitory control, working memory, and cognitive flexibility. Higher-order EFs such as reasoning, problem-solving, and planning are formed from those.<br />As these abilities are essential for continuing social and cognitive development and academic achievement, it is crucial to optimize methods for assessing these skills in children, and pinpointing potential deficits in order to design appropriate remediation measures.<br />This highlights the need for a comprehensive Arabic tool to tackle more detailed parts of the executive function deficits.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301A PROSPECTIVE COMPARISON STUDY BETWEENBEDSIDE ULTRASONOGRAPHY AND COMPUTED TOMOGRAPHY OF THE CHEST FOR THE DIAGNOSIS OF PNEUMONIA IN EMERGENCY DEPARTMENT4513578610.21608/alexpo.2021.56327.1101ENRana MoursiAmerdepartment of emergency medicine,faculty of medicine, alexandria universityJournal Article20210103Pneumonia is considered a major healthcare problem that has a huge effect on the morbidity and mortality globally. It is considered one of the leading causes of death worldwide. <br />Any delay or failure in the diagnosis or management of pneumonia causes significant increase in mortality. Meanwhile, inappropriate antibiotic leads to the development of antibiotic resistance.<br />Traditionally, the diagnosis of pneumonia is reached using clinical examination, laboratory data, radiological techniques, and cultures. Clinical information alone is not enough to predict pneumonia. <br />Chest X-ray (CXR) is the easiest approach in patients with suspected pneumonia, in search for a new infiltrate. However, studies clarified that it has low sensitivity for the diagnosis of pneumonia in comparison to chest computed tomography (CT). But the use of chest CT is not commonly used except for complex cases and cases with failure response to treatment. Lung ultrasonography (LUS), being a fast bedside technique, it has attracted many interests to preform studies to assess its ability to detect pleuropulmonary pathologies generally and pneumonia specifically.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301VALUE OF LUNG ULTRASOUND IN ASSESSMENT OF PEDIATRIC PATIENTS WITH PNEUMONIA VERSUS CHEST PLAIN X- RAY5613625510.21608/alexpo.2021.55825.1097ENSarah El HussinyAbdel FattahDepartment of Radiodiagnosis, Faculty of Medicine, Alexandria UniversityJournal Article20201230Community acquired pneumonia (CAP) is defined as an infectious pneumonia that is acquired outside or inside the hospital in children without immune damage.<br />Radiographic findings:<br />Chest X-ray (CXR) has been the main modality in the investigation of chest infection since it has been invented in the late 19th century.<br />CXR has certain restrictions such as radiation exposure risks, high inter-observer and intra- observer variations, and little impact on the clinical outcomes. Children in comparison to adults have 3 to 5 times higher morbidity and mortality risk from radiation exposure. <br />A call for new imaging modality which is “lung ultrasonography”:<br />LUS findings were classified as a normal pattern, defined as normal lung sliding with or without A-lines or having the following according to the following Ultrasonographic signs of pneumonia: <br />1. Presence of subpleural lung Alveolar consolidations: subpleural echo-poor regions or tissue-like region, with blurred margins irregular borders “shred sign” in nontranslobar consolidation, or lung hepatization in translobar consolidation. <br />2. Air bronchogram: branching hyperechoic structures in the consolidation. Lentiform or punctiform air bronchogram were not counted as separate signs and were considered as part of the consolidation. <br />3. Presence of B-lines. <br />4. Pleural line abnormalities, defined as irregularities in the pleural line. <br />5. Pleural effusion defined as anechoic or hypoechoic fluid with or without floating debris.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301COMPARISON BETWEEN LOW AND HIGH DOSES OF PROPHYLACTIC VITAMIN D IN PREVENTION OF OSTEOPENIA OF PREMATURITY6713625810.21608/alexpo.2021.56120.1100ENMoataz AhmedRezkPediatrics, Alexandria faculty of medicine, Alexandria, EgyptJournal Article20210101Osteopenia of prematurity (OOP) is a term used to describe a reduction in bone mineral content (BMC) of the preterm infant. Its incidence has been steadily increasing with the survival of more premature neonates as a result of advances in neonatal care. The prevalence of metabolic bone disease is inversely associated with birth weight and gestational age. Up to a third of infants weighing less than one kilogram at birth are osteopenic, more so if they are breastfed.<br />To develop normally, the skeleton of the fetus requires active materno-fetal transfer of protein, Calcium (Ca) and phosphorus (P). Bone mineralization which occurs predominantly during the third trimester will be inadequate if the fetal increased demands in Ca and P are not met. During pregnancy augmented maternal intestinal absorption and increased skeletal mobilization increase maternal Ca supply to the fetus.<br />Factors that impede normal bone mineralization include inadequate postnatal intake of vitamin D, calcium (Ca) and phosphorus (P), extended periods of total parenteral nutrition, and also as a side effect of diuretics and corticosteroids prescribed to these infants. Poor bone mineralization is associated with common neonatal conditions. These include sepsis, bronchopulmonary dysplasia, cerebral pathology, acidosis, necrotizing enterocolitis and cholestasis.<br />Depending on the severity of the demineralization, osteopenia can remain clinically silent or, if severe, can cause bone changes in the form of rarefaction, fraying, cupping, subperiosteal new bone formation or even fractures.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301EFFECT OF PHACOEMULCIFICATION ON RETINAL NERVE FIBER LAYER IMAGING USING OCULAR SPECTRAL DOMAIN COHERENT TOMOGRAPHY7813647810.21608/alexpo.2021.54173.1088ENMoustafa Abd El HalimRoushdyDepartment of Ophthalmology, Faculty of Medicine, University of AlexandriaJournal Article20201219OCT uses light reflectance signal from the retina to measure RNFL thickness. Several software programs are there to perform segmentation of RNFL automatically by detecting the internal limiting layer and outer RNFL. <br />OCT imaging is influenced by cataract; image quality is reduced preoperatively and RNFL thickness measurements are slightly increased postoperatively. In individual patients, OCT scans remain reliable for gross clinical interpretation, even in the presence of cataract. <br />OCT imaging relies on near-infrared light. Similar to its effects in fundus photography and scanning laser ophthalmoscopy, a cataract is likely to increase light scattering and degrade OCT image quality. Some authors have reported variations in OCT measurements before and after uncomplicated cataract surgery, but these studies included only short series of healthy subjects and focused on a slight increase in retinal thickness after surgery, and on the apparent increase in RNFL thickness due to the resulting improved image quality.<br />Ultrasonic energy and fluidics produce mechanical effects that cause an inflammatory reaction that should also be taken into account as a risk factor that may affect the structure of the tissue in the eyeball.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301PATERN AND TREND OF INTERNET ADDICTION DISORDER AMONG MEDICAL STUDENTS IN ALEXANDRIA: A CROSS SECTIONAL STUDY8913731010.21608/alexpo.2021.55841.1098ENHend IbrahimKamelDepartment of Community Medicine , Alexandria Faculty of Medicine, EgyptJournal Article20201230The Internet itself is designed to facilitate research among academic & military agencies. The internet usage has been rapidly increasing worldwide and has become an integral part of day-to-day life. College students are vulnerable because of the psychological and developmental characteristics of late adolescence & ready access to the internet. The internet addiction disorder (IAD) is a new kind of mental illness characterized by excessive, constant and misuse of the internet recognized by adverse reaction and compulsive behavior. Accordingly, familial, academic and occupational problems are the negative consequences.<br />Aims of the work<br />To reveal the prevalence, pattern, trend and the related factors of IAD. To explore the association between the IAD, negative consequences and the academic achievements of Alexandrian medical students. <br />Subjects and Methods<br />Research strategy: <br />In order to achieve the research objectives, a stratified cross-sectional study was carried out<br /> Research settings: <br />Faculty Of Medicine, Alexandria University during the academic year 2018/2019.<br /> Target population: <br />Consented 400 students namely; undergraduates (from 1st to 6th year and intern) and postgraduates (fresh graduated tutors). <br />Data collection tools and methods<br />Self-administered semi-structured questionnaire consisting of data about: <br />1- Socio-demographic personal characters & academic achievement in the previous year.<br />II. Internet use:<br />A. Knowledge, attitudes & practice.<br />B. Negative consequences (adverse reaction)<br />III. The Young's Internet Addiction Test (IAT):Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301COMPARISON OF EARLY POSTOPERATIVE RESULTS OF ON-PUMP VERSUS OFF-PUMP CORONARY BYPASS GRAFTING SURGERY91013752010.21608/alexpo.2021.56871.1104ENHanan MamdouhHemeadDepartment of Cardiothoracic Surgery, Alexandria University, Alexandria, EgyptJournal Article20210106Assisted by cardiopulmonary machine (CPB), CABG surgery is performed safely with excellent outcomes. Due to the adverse events linked to the CPB, the off-pump CABG becomes an acceptable alternative particularly in patients with calcified proximal aorta. Critics of off-pump CABG often refer to the long learning curve and difficult building cumulative surgical experience. Off-pump CABG has been always a matter of debate. Off-pump CABG becomes highly appealing due to minimal invasiveness of the procedure, suitability to some population and better early outcomes.<br />Aim: <br />This study evaluates the early postoperative outcomes of off-pump CABG compared to on-pump CABG.<br />Subjects& methods:<br />First eligible comers in the period between 2018-2019.The following points were compared between the two groups Amount of bleeding, length of stay, duration of mechanical ventilation, operative time, completion of revascularization, complications; atrial fibrillation, neurological deficits, acute kidney injury.<br />Conclusion:<br />The argument surrounding the potential advantages and safety of the off-pump is difficult to be settled. Off-pump CABG, in the hands of trained surgeons, offers favorable short-term outcomes particularly in patients with complex co-morbidities. It is highly indicated in heavily calcified aorta to avoid the thromboembolic events.The decision should be made on individual basis, taking into consideration the potential long-term adverse outcomes.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301LOOP TRANSVERSE COLOSTOMY VERSUS LOOP IELOSTOMY FOR DEFUNCTIONING OF COLORECTAL AND COLOANAL ANASTOMOSIS: A RANDOMISED PROSPECTIVE STUDY101113807910.21608/alexpo.2021.57391.1105ENKarim MahmoudShenitdepartment of colorectal surgery Alexandria universityJournal Article20210110The change in the paradigm that started with the introduction of total mesorectal excision (TME) by Heald dramatically increased the rate of sphincter-preserving low-anterior resection.TME became accepted as a standard procedure because of the observed low recurrence rate and prolonged survival<br />The incidence of symptomatic anastomotic leakage after anterior resection and TME was reduced by the defunctioning loop stoma but There is still some debate as to whether loop transverse colostomy or loop ileostomy is the correct way of defunctioning such anastomosis<br />Is to compare loop transverse colostomy versus loop ileostomy for defunctionning of colorectal and coloanal anastomosis<br />This is aprospective study that included forty patients that were diagnosed with rectal cancerandadmitted to colorectal surgery unit and Patients were divided into two groups randomly, one group was subjected to loop transverse colostomy (group A) and the other group was subjected to loop ileostomy(group B).<br />We compared both groups as regard: operative time, post-operative complications, postoperative quality of life,and stoma reversal complication. The mean period of follow up was three months postoperative.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301RECONSTRUCTION OF MARGINAL AURICULAR DEFECTS USING CHONDROCUTANEOUS HELICAL RIM ADVANCEMENT FLAP111213854910.21608/alexpo.2021.55700.1095ENMohamed Elsayed Mohamed GadelrabBakryPlastic and reconstructive surgery, Faculty of Medicine, Alexandria UniversityJournal Article20201229Ear reconstruction is a challenging process owing to the sophisticated anatomy of the ear.The aim of facial plastic surgeons is to restore the ultimate aesthetic shape of the ear according to the anatomical considerations as smooth external contours, surface standards, and the proper physical dimensions and to ensure contentment of the patient.<br />The auricle is most commonly associated with congenital abnormalities.Traumatic damages and pathologic disorders, especially cancer may cause acquired defects of the auricle.<br />The chondrocutaneous helical rim advancement flap (CHRAF) described by Antia and Buchis a good method of reconstructing defects of the helix and the modifications that have been reported broadened the scope of its use to large defects and defects extend beyond the helix <br />A variant of CHRAF includes a pedicle flap based on ear lobule providing blood supply (axial) to the flap named Ear Lobe Based Flap.<br />Aim of the work<br />The aim of this studywas to assess the versatility of the chondrocutaneous helical rim advancement flap with its different modifications when needed for the reconstruction of marginal auricular defects that include the helix alone or may extend onto the scapha, antihelix, and triangular fossa.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301EVALUATION OF THE ROLE OF INTERVENTIONAL RADILOGY TECHNIQUES IN THE MANAGEMENT OF THE COMPLICATIONS OF PANCREATITIS121313869110.21608/alexpo.2021.56859.1103ENMohamed AdelGouharradiodiagnosis department, faculty of medicine, Alexandria universitySherif AlsayedHegabProfessor of Radiodiagnosis, Faculty of Medicine, University of AlexandriaMohsen AhmedAbdelmohsenlecturer of radiodiagnosis department, faculty of medicine, Alexandria universityJournal Article20210106In the treatment of local complications of pancreatitis no universally accepted algorithm currently exists. The approach often is dictated by the expertise of the surgeon and the interventional radiologist. The clinical status of the patient (eg, presence of sepsis, systemic inflammatory response syndrome, multisystem organ failure or acute haemorrhage) often determines the approach to be taken.<br />Image-guided drainage procedures have proved to be effective alternatives to surgery, particularly early in the course of complications from severe acute pancreatitis with necrosis. Some of these percutaneous procedures are performed to stabilize seriously ill patients before surgery (bridge care), and others are intended to cure.<br />Interventional radiology also is called for ancillary procedure. Pseudoaneurysms or active bleeding related to acute pancreatitis are usually diagnosed on the basis of contrast enhanced CT findings, and images should be obtained in late arterial and portal venous phases.<br />Interventional <br />Interventional radiology plays an increasing, crucial role in the multidisciplinary management of complications pancreatitis. It provides a minimally invasive therapy also in critical patients, reducing recovery times and avoiding operation morbidity.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301A COMPARATIVE POLYSOMNOGRPHIC STUDY BETWEEN PATIENTS WITH WAKE UP AND DAYTIME ISCHEMIC STROKE ADMITTED AT ALEXANDRIA UNIVERSITY HOSPITALS131414091210.21608/alexpo.2021.58258.1106ENAkram FawzyMohamedDepartment of Neurology and Psychiatry, Faculty of Medicine, University of Alexandria, Egypt.Journal Article20210116Cerebrovascular stroke and sleep are closely correlated.1 Several pathophysiological mechanisms have been proposed in the literature that explain the occurrence of a stroke at high rates with certain sleep disorders.2 <br />Obstructive sleep apnea (OSA) is on the top of the list of sleep disorders increasing the risk for cerebrovascular stroke.3 Obstructive sleep apnea increases stroke risk via several direct and indirect mechanisms. Direct mechanisms include increased sympathetic activity, nocturnal hypertension, intermittent hypoxia, arousal responses, hemodynamic instability, oxidative stress, and endothelial dysfunction.4 Indirect mechanisms include increasing the risk for other stroke risk factors such as diabetes mellitus, hypertension, and cardiac arrhythmias. Insomnia, periodic limb movements (PML), and restless leg syndrome (RLS) are other sleep disorders that increase stroke risk. They were proposed to increase the stroke risk via increasing sympathetic activity, micro-arousals, oxidative stress, oxidative stress, hypoxia, inflammation, and metabolic dysregulation. Sleep duration was also reported to be related to stroke. Both long and short sleep duration were reported to increase sleep risk.5<br />Though the relationship between stroke and sleep is well established, data is scarce about the correlation between sleep architecture and stroke time onset. The sleep architecture was compared between patients with wake-up stroke (WUS) and patients with daytime stroke (DTS) in few studies literature studies, and the data from these studies are conflicting.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301THE ADDED VALUE OF THREE DIMENSION DOUBLE INVERSION RECOVERY MAGNETIC RESONANCE SEQUENCE IN DETECTION OF BRAIN LESIONS IN MULTIPLE SCLEROSIS PATIENTS141514221710.21608/alexpo.2021.53860.1087ENTasneem MOLHAMAbdellateefDepartment of radiodiagnosisJournal Article20210109Multiple sclerosis (MS) is the most prevalent chronic inflammatory disease of the central nervous system (CNS), affecting more than two million people worldwide and characterized by the presence of multifocal inflammatory demyelinating lesions disseminated in space and in time.<br />MS lesions may occur in any part of the CNS where myelin exists, but lesions around the ventricles and the corpus callosum are highly suggestive.<br />High MRI sensitivity in the depiction of plaques in the brain and spinal cord has made this technique the most valuable para-clinical tool for the diagnosis of multiple sclerosis (MS)<br />Cortical grey matter lesions occur abundantly in MS across all disease courses and are correlated with clinical manifestations, therefore, adding them as diagnostic criteria improves their specificity and reduce misdiagnosis. 2017 revision the panel recommended that, cortical lesions, in addition to sub-cortical lesions can be used to fulfil MRI criteria for DIS. <br />3D double inversion recovery (3D-DIR) is a new MR sequence, assumed to detect more cortical lesions than conventional sequences, which can be more specific for MS diagnosis and may allow better differentiation from MS mimics.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301PELVIC FLOOR MUSCLE TRAINING USING BIOFEEDBACK THERAPY VERSUS BILATERAL POSTERIOR TIBIAL NERVE STIMULATION FOR TREATMENT OF OBSTRUCTED DEFECATION A RANDOMISED CONTROLLED TRIAL151614265710.21608/alexpo.2021.59002.1109ENFouad MohamedAshoushDepartment of Surgery, Faculty of Medicine, Alexandria UniversityJournal Article20210120Obstructed defecation syndrome (ODS) is a type of constipation characterized by two or more of the following symptoms in more than 25 percent of defecation trials: straining, lumpy or hard stools, urgency, sense of incomplete evacuation, pelvic heaviness and manual maneuvers to promote defecation.<br />obstructed defecation is of two basic types: functional and mechanical. The functional type involves idiopathic megarectum, anismus (pelvic floor dys-synergy), and descending perineal syndrome, while the mechanical type includes rectocele, enterocele, internal rectal intussusception and overt rectal prolapse.<br />An excessive straining is likely to be the “primummovens”, causing tissue weakness and organ descent, and often is due to longterm anxiety, muscle tension and resulting in non-relaxing puborectalis muscle. The increased straining causes pudendal nerve stretch which may lead to a pudendal neuropathy which affects the rectal sensations.<br />ODS has been also defined as an “iceberg syndrome”, as the two most frequent lesions, i.e., rectocele and rectal internal mucosal prolapse, present in more than 90% of patients with ODS, are easily detectable and may be considered “emerging rocks”, whereas the “surgical ship” is likely to “sink” due to the “underwater rocks”, i.e., the occult lesions.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301ADDED VALUE OF POSITRON EMISSION TOMOGRAPHY/ COMPUTED TOMOGRAPHY IN DETECTION OF PERITONEAL CARCINOMATOSIS161714265810.21608/alexpo.2021.59106.1110ENOla MohamedHaggagDepartment of Radiodiagnosis and Intervention, Faculty of Medicine, Alexandria University, Ministry of HealthJournal Article20210121The peritoneum consists of 2 layers the parietal layer covering the inner surface of abdomen and visceral layer which reflects over and surround the abdominal organs. Peritoneal carcinomatosis is one of the frequent sites of metastasis in many gastrointestinal and gynecological tumors mostly colorectal and ovarian cancer. <br />Various forms of peritoneal carcinomatosis could be noted in the form of ascites, micronodular, nodular, plaque like, mass like, omental cake, teca aspect and ileal freezing.<br />Positron emission tomography (PET) is being increasingly used for diagnosis, staging, and follow-up of various malignancies. In peritoneal carcinomatosis, FDG-PET/CT has been shown to have higher sensitivity and positive predictive value (up to 92%) compared to FDG-PET and CT alone. It also has higher specificity (up to 97%) compared to FDG-PET alone, with similar specificity compared to CT alone. It is more useful than just PET the addition of CT allows better anatomic visualization and can detect the presence of cancer lesions based on the glucose uptake of the cells. It identifies the exact localization and area of the peritoneal metastasis, PET-CT provides better accuracy. It adds good value to the conventional imaging mainly for monitoring response to the therapy, especially on long-term follow-up. <br />PET/CT has multiple clinical applications in peritoneal oncology detecting the primary tumor in unknown primary, tumor staging and restaging; treatment planning, post therapy response, differentiating recurrence from post therapy changes; distinguishing malignant from benign peritoneal disease; can be used as a biomarker as well as alternative tracers for cancer evaluation.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301Sensitivity and specificity of three-point compression ultrasonography test performed by emergency physicians for diagnosis of lower limbsdeep venous thrombosis171814340710.21608/alexpo.2021.58778.1108ENEman HelmiEl-GazzarDepartment of emergency medicine, faculty of medicine university of AlexandriaJournal Article20210119 Deep vein thrombosis (DVT) is defined as development of thrombosis within the deep veins of the pelvis or lower limbs.<br /> Thrombus formation is a dynamic, multifactorial process that depends on a fine balance of physical and biochemical factors. The causes of thrombosis include three main causes: vessel wall injury, hypercoagulability, and venous stasis which is known as Virchow’s triad.<br /> Early detection of deep venous thrombosis is very important not only to initiate anticoagulant therapy, but also very important to prevent further complications and to reduce morbidity and mortality.<br /> Diagnosis of DVT depends on clinical examination, laboratory and radiological investigations.<br /> Development of DVT is affected by many factors either genetic or acquired risk factors like age, Trauma, Cancer, Surgery, Pregnancy, Obesity, Immobility, hospitalization, hormonal therapy, inherited and acquired hypercoagulable states, anaesthesia, myocardial infarction, history of DVT, varicose veins, infections, inflammatory bowel disease, dehydration, and renal impairment are common risk factors. <br /> Compression ultrasonography is the first-line imaging tool for diagnosis of DVT because it is safe, easily accessible, cost-effective, and reliable.It is accurate to determine the size, chronicity, and degree of occlusion ofthrombus which is very helpful for making the decision of starting medical management or interventional techniques.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301SURGIAL VERSUS ULTRASOUND GUIDED ASPIRATION OR DRAINAGE OF DEEP NECK SPACE ABSCESSES: A RANDOMIZED CONTROLLED TRIAL181914357710.21608/alexpo.2021.57390.1111ENAbdelrahman MostafaHassanDepartment of Otorhinolaryngology , faculty of medicine ,university of alexandriaAlaa HazemGaafarENT department , faculty of medicine , Alexandria universityJournal Article20210124Deep neck space abscesses are considered to be one of the life-threatening emergencies in the head and neck region. Traditionally, the main treatment for deep neck space abscesses was surgical drainage with sufficient antimicrobial treatment. Intraoral or external approaches can be used for surgical drainage of neck abscesses. Despite the effectiveness of these procedures, they have some remarkable disadvantages. General anesthesia is required, which add a considerable risk for patients especially those with bad general condition. Intraoral approaches have their limitations like poor visualization and airway compromise. External approaches usually necessitate neck incisions and exploration, which exposes patients to a risk of injury to vital neurovascular structures and a cosmetically unpleasant scar.<br />Recent literature suggested a less invasive and an effective alternative to surgical incision and drainage by performing ultrasound-guided drainage of neck abscesses. It abolishes most of the drawbacks of incision and drainage and has been proven to be effective in certain cases.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301Role of Serum level of IL-1B and MMP-13 in detection of severity and functional impairment in hand Osteoarthritis patients192014453210.21608/alexpo.2021.59555.1113ENSalma ElsayedAbdelghaneyphysical medecine ,rheumatology and rehabilitation departement, faculty of medecine, alexandria university, alexandria, egyptAbd El Moneim HusseinHelalDepartment of Physical Medicine, Rheumatology and Rehabilitation, Faculty of medicine, Alexandria university, Egypt.Diaa FahmyMohassebPhysical medicine, Rheumatology and Rehabilitation, Faculty of medicine, Alexandria University, Alexandria, EgyptYousra HishamAbdel FattahDepartment of Physical Medicine, Rheumatology and Rehabilitation, Faculty of medicine, Alexandria university, Egypt.0000-0002-5692-3483Salma Alaa EldinImbabyDepartment of clinical pathology, Faculty of medicine, Alexandria university, Egypt.Journal Article20210126Hand Osteoarthritis (HOA) is one of the most common chronic degenerative joint diseases. Pain and decreased function are the leading symptom in HOA. Previously HOA was considered a pure degenerative disease, but this concept has changed and current research has demonstrated that inflammation is one of the key factors leading to the cartilage destruction. Cytokines as Interleukin-1β (IL1- β) induces expression and release of proteolytic enzymes such as matrix metalloproteinases (MMPs) and aggrecanases. Chondrocyte-derived MMPs are the main enzymes involved in the breakdown of cartilage collagens and proteoglycans. Research in the area of Hand OA is important to help early diagnosis, stop the progression of the disease, and preventing disability.The aim was to determine role of serum level of IL-1β and MMP-13 in detection of severity and functional impairment in patients with HOA.The study was carried out on 30 patients diagnosed with HOA, fulfilling the ACR 1990 criteria for diagnosis of HOA. Demographic data and anthropometric measurements were recorded for all participants. <br />Clinical characteristics of the disease including duration of disease, pattern of joint involvement, pain and disease severity as well as functional assessment of HOA were assessed. Radiographic severity of HOA was assessed by Kellgren and Lawrence (K-L) score. Serum IL-1β and MMP-13 were assessed using double-antibody sandwich enzyme-linked immunosorbent assay method in both patients and control.The conclusion was that Interleukin-1B and MMP-13 seem to have an insignificant role in detection of severity and functional impairment in mild to moderate HOA.Alexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301SERUM LEVELS OF ACTIVE COMPLEMENT C3 AND C4 IN PRE- ECLAMPTIC AND NORMOTENSIVE CASES AND THEIR CORRELATION TO FETAL AND MATERNAL OUTCOME202114546410.21608/alexpo.2021.59733.1112ENAsmaa SalihAbdulshafiaFaculty of omar almokhtar libya 2008Journal Article20210125Preeclampsia is a syndrome diagnosed by hypertension and proteinuria after 20 weeks of gestation; it affects 5–10% of all pregnancies and remains a leading cause of maternal and fetal morbidity and mortality. Based on clinical presentation, preeclampsia is considered as a late pregnancy disorder, but the molecular events leading to its onset seem to occur early in pregnancy. The early phase of the disease is characterized by suboptimal placentation and hemodynamic maladaptation to the pregnancy while at later stages generalized vascular dysfunction leading to clinical syndrome of preeclampsia, Maternal symptoms of preeclampsia are considered consequences of placental pathology associated with poor placental perfusion, inflammation and ischemia / hypoxia,trophoblast damageand activation of complement pathways either classical or alternative pathway.the activation of the complement system plays an important role both in maintaining normal pregnancy and in the pathogenesis of pre‐eclampsia, activation of both classical and alternative pathways plays an important role in cleaning up the numerous trophoblastic cell fragments formed during the placental establishment process. If the complement system is over activated, however, the activating complement component C3a and C4a can activate a maternal systemic inflammatory response, leading to the corresponding manifestations of pre‐eclampsiaAlexandria University, Faculty of MedicineALEXMED ePosters2682-26363120210301COMPARING HEARING AID FITTING OF THE MANUFACTURER'S FIRST FIT VERSUS NAL-NL2 USING REAL EAR MEASUREMENTS212214629010.21608/alexpo.2021.60879.1116ENHeba Gamal EldinSharakyaAudio-vestibular Medicine Unit, Department of Otorhinolaryngology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.Journal Article20210201Real ear measurments (REMs) or the probe microphone measurments is an objective method to verify hearing aids fitting taking into account the ear canal acoustics of the patient.(1) It is the best method to provide a patient with an audible signal.(2)<br />Prescriptive fitting formulas, such as NAL-NL1, NAL-NL2, and DSL V5a are evidence-based methods for determining how much amplification is needed for a particular hearing loss. By using prescriptive formula verified with REMs at the initial hearing aid fitting allows the audiologist to ensure audibility for conversational speech, to set appropriate amounts of amplification for soft sounds, and to prevent loud sounds from becoming uncomfortable.(3) <br />Some audiologists use the first-fit formulas of the manufacturer to have a proper fitting gain, however, many studies revealed that the first fit of the manufacturer is insufficient for the required gain.(4)<br />Self-report outcome measure is also mandatory to determine the benefit of hearing aids.(5) The Abbreviated Profile of Hearing Aid Benefit questionnaire (APHAB) is used to measure disability caused by hearing loss and measure the reduction of that disability by using hearing aids. The APHAB uses 24 elements including 4 dimensions: ease of communication, reverberation, background noise, and aversiveness to sounds.(6)